Results 51 to 60 of about 2,125 (258)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Frontiers in Psychology, 2019 Negative Concord (NC) constructions such as the news anchor didn’t warn nobody about the floods (meaning “the news anchor warned nobody”), in which two syntactic negations contribute a single semantic one, are stigmatized in English, while their Negative
Frances Blanchette, Cynthia Lukyanenko
doaj +1 more source
Reports on Mathematical Logic, 2018 In this paper we isolate a property for forcing notions, the *-Prikry condition, that is similar to the Prikry condition but that is topological: A forcing P satisfies it iff for every p ∈ P and for every open dense D ⊆ P, there are n ∈ ω and q ≤∗ p such that for any r ≤ q with l(r) = l(q) + n, r ∈ D, for some length notion l.
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández +10 more
wiley +1 more source
Arthritis Care &Research, EarlyView.People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Advanced Engineering Materials, EarlyView.A two‐dimensional multiscale finite element analysis framework was established for the first‐generation MoSiBTiC alloy, and the mechanical and fracture‐related parameters of the constituent phases were calibrated through experiments and simulations. The framework provides a basis for analyzing crack propagation behavior in its complex microstructure ...
Junfeng Du +4 more
wiley +1 more source
MODUS PONENS AND MODUS TOLLENS: THEIR VALIDITY/INVALIDITY IN NATURAL LANGUAGE ARGUMENTS
Studies in Logic, Grammar and Rhetoric, 2017 The precedent studies on the validity of Modus ponens and Modus tollens have been carried out with most regard to a major type of conditionals in which the conditional clause is a sufficient condition for the main clause.
Ri Yong-Sok
doaj +1 more source
Machine Learning‐Assisted Inverse Design of Soft and Multifunctional Hybrid Liquid Metal Composites
Advanced Functional Materials, EarlyView.A machine learning framework is presented for inverse design of synthesizable multifunctional composites containing both liquid metal and solid inclusions. By integrating physics‐based modeling, data‐driven prediction, and Bayesian optimization, the approach enables intelligent design of experiments to identify optimal compositions and realize these ...
Lijun Zhou +5 more
wiley +1 more source
Actuality and fake tense in conditionals
Semantics and Pragmatics, 2015 Sabine Iatridou (2000) and Katrin Schulz (2014) defend accounts of the past tense in subjunctive conditionals according to which the past tense has a modal reading that excludes the world of utterance or some set of epistemically possible worlds. I argue
John Mackay
doaj +1 more source