Results 101 to 110 of about 2,348,563 (303)

Concentration of various angiogenesis related factors in the conditioned medium of hDPSC (as determined by ELISA).

open access: yes, 2013
Values are represented as mean ± S.E.M. (n≥3). CM = conditioned medium.
Yanick Fanton (442677)   +7 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Quantification of octeoclasts induced by conditioned medium derived from PCa cells.

open access: yes, 2013
Quantification of octeoclasts induced by conditioned medium derived from PCa cells.
David J. DeGraff (323519)   +6 more
core   +1 more source

Expression of Procollagen A1 Type I Induced by Two Different Dentine Bonding Systems in Human Pulp Fibroblasts

open access: yesEuropean Journal of Inflammation, 2013
This study aimed to evaluate the effects of two different dentine bonding systems (DBSs) on primary cultures of human pulp fibroblasts (HPFs). Cell viability and procollagen α1 type I expression were investigated.
G. Orsini   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Screening MPC growth- and differentiation-conditioned medium in MBAs.

open access: yes, 2013
A Traces of ELF97/DNA expression index against row, from column 1 of all microbioreactor runs from Figure 2 (pooled arrays), and the average value. B Panel of conditions formed in conditioned medium screening experiment.
Harish Padmanabhan (501142)   +3 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

POTENSI TRANSDIFERENSIASI SEL FIBROBLAS MENJADI SEL SARAF SECARA IN VITRO (Transdifferentiation Potency of Fibroblast Cell to Neuron Cell in Vitro)

open access: yesJurnal Kedokteran Hewan, 2016
The aim of this study was to examine the potency of fibroblast cells transdifferentiated to neuron cells in vitro. Newborn rat neuron conditioned medium (NBRN CM) was collected from neuron cells cultured with mDMEM without serum for 48 hours.
Ekayanti M. Kaiin, Ita Djuwita
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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