Results 121 to 130 of about 540,654 (303)

L929 CONDITIONED MEDIUM (LCM) v1

Macrophage colony stimulating factors (M-CSF) are secreted by L929 cells (ATCC) and promote bone marrow progenitors to differentiate into a heterogeneous population of bone marrow derived macrophages (BMDM) expressing various myeloid surface markers (CD11b, F4/80, BM8, CD31, CD68, CD11c, Ly6C, GR1 ...
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Investigating the Effect of Co-culturing Human Adipose-Derived Stem Cells on Retinal Cells Survival and Migration in Vitro Environment

مجله دانشکده پزشکی اصفهان, 2017
Background: Human adipose-derived stem cells (hADSCs) are population of cells isolated from adipose tissue. hADSCs have ability to differentiate along multiple cell lineages and secret verity of growth factors, which affect the neighboring cells ...
Leila Naseri, Noushin Amirpour, Hamid Bahramian, Hossein Salehi   +3 more
doaj  

Dual effect of monocyte-conditioned medium on in vitro hematopoiesis [PDF]

, 1984
Thesis--University of Tsukuba, D.M.S.(B), no. 221, 1989. 10. 31Offprint. Originally published in: Experimental hematology, v. 10, no. 7, pp.
Abe Tsukasa, Hanada Takashi, Nagasawa Toshiro   +2 more
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Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Serum-free spontaneously immortalized bovine oviduct epithelial cell conditioned medium promotes the early development of bovine in vitro fertilized embryos

The Journal of Reproduction and Development
Embryonic transfer of bovine blastocysts produced using in vitro fertilization (IVF) is widely used, although the challenge of compromised conception rates remains.
Norikazu MIYASHITA, Satoshi AKAGI, Tamas SOMFAI, Yuji HIRAO   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Conditioned serum-free culture medium accomplishes adhesion and proliferation of bovine myogenic cells on uncoated dishes

npj Science of Food
To establish a sustainable cultured meat technology, a low-cost culture medium must be developed without expensive biological materials such as serum and coating substances.
Takashi Morikura, Katsuhisa Sakaguchi, Ryu-ichiro Tanaka, Azumi Yoshida, Hironobu Takahashi, Kiyotaka Iwasaki, Tatsuya Shimizu   +6 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

PAR1 activation induces the release by Schwann cells of factors promoting cell survival and neuritogenesis [PDF]

, 2017
Protease-activated receptor 1 (PAR1) is a member of a family of four G-protein-coupled receptors which are activated by proteolytic cleavage of their N-terminal extracellular domain.
Artico, M., Ciraci, V., Correani, V., Fabrizi, C., Fumagalli, L., Maras, B., Pompili, E., Schininà, M. E.   +7 more
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