Results 241 to 250 of about 540,654 (303)

Therapeutic Effects of Stem Cells from Human Exfoliated Deciduous Teeth and Their Conditioned Medium in Cisplatin-Induced Acute Kidney Injury: An In Vivo Study. [PDF]

Biology (Basel)
Talebi A, Talebi S, Nikpoor S, Nourbakhsh N, Talebi H, Soroushzadeh S, Gómez-Polo M, Mosaddad SA.   +7 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Application of dental pulp stem cell-conditioned medium combined with deep cryopreservation of autologous cranial flaps. [PDF]

Stem Cell Res Ther
Liu Y, Liu Y, Ye Z, Wang X, Li J, Mei PL, Duan L, Wang B, Xu C, Xiong W, He Y, Ye Q.   +11 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Improving Bovine Embryo Development and Quality Using Bovine Oviductal Epithelial Cell-Derived Conditioned Medium (bOEC-CM). [PDF]

Vet Med Sci
Hosseinabadi SK, Nazari H, Arabi M, Shams Esfandabadi N, Ahmadi E, Afzali A, Ghanaei H.   +6 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Evaluation of conditioned medium from Sertoli cells as a potential inducer of <i>in vitro</i> germ cell differentiation of bovine fetal mesenchymal stem cells (MSCs). [PDF]

Anim Reprod
Leiva B, Cortez J, Segunda M, Torres C, Escobar A, Diaz C, Peralta O.   +6 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Direct Identification and Quantification of Recombinant Adeno-Associated Virus in Crude Cell Lysate and Conditioned Medium by Mass Photometry. [PDF]

Anal Chem
Yamaguchi Y, Shimojo S, Shibuya R, Bandoh K, Matsushita A, Fukuhara M, Tsunaka Y, Torisu T, Uchiyama S.   +8 more
europepmc   +1 more source

Skin Telocyte Secretome as Conditioned Medium Prevents Profibrotic Differentiation of Skin Fibroblasts into Myofibroblasts. [PDF]

Int J Mol Sci
Rosa I, Fioretto BS, Andreucci E, Biagioni A, Romano E, Manetti M.   +5 more
europepmc   +1 more source