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What's conditioned in conditioned place preference?
Trends in Pharmacological Sciences, 2013Conditioned place preference (CPP) is a learned behavior shown in many vertebrates, including humans. CPP occurs when a subject comes to prefer one place more than others because the preferred location has been paired previously with rewarding events.
Joseph P, Huston +3 more
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Nicotine-induced conditioned place preference and conditioned place aversion in mice
Pharmacology Biochemistry and Behavior, 1995The motivational effects of nicotine were examined in mice using an unbiased place conditioning design. Swiss-Webster mice received four 15-min parings of a tactile stimulus with different doses of nicotine (0.25-2.0 mg/kg, IP). A different tactile stimulus was paired with saline injections.
F O, Risinger, R A, Oakes
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Conditioned place preference produced by the psychostimulant cathinone
European Journal of Pharmacology, 1993Previous work has indicated that the psychostimulant cathinone produces a location preference in the conditioned place preference task. The present study expanded upon this earlier work by examining the dose-response nature of cathinone-induced conditioned place preference, as well as testing its effect upon spontaneous locomotor activity.
Martin D Schechter +2 more
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Journal of Psychopharmacology, 1992
Chronic exposure to very mild unpredictable stress has previously been found to reduce or abolish the acquisition of place preference conditioning. In the present study, chronic mild stress was found to abolish the acquisition of preferences for a distinctive environment paired with morphine (0.7 mg/kg).
M, Papp +3 more
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Chronic exposure to very mild unpredictable stress has previously been found to reduce or abolish the acquisition of place preference conditioning. In the present study, chronic mild stress was found to abolish the acquisition of preferences for a distinctive environment paired with morphine (0.7 mg/kg).
M, Papp +3 more
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Pharmacology Biochemistry and Behavior, 2000
In two experiments, we report that the place-conditioning paradigm can be used to demonstrate reinstatement of place preference/aversion by a drug prime following extinction training. In Experiment 1, rats were trained to prefer a chamber paired with morphine. Following extinction training, a morphine drug prime reinstated the morphine place preference.
L A, Parker, R V, Mcdonald
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In two experiments, we report that the place-conditioning paradigm can be used to demonstrate reinstatement of place preference/aversion by a drug prime following extinction training. In Experiment 1, rats were trained to prefer a chamber paired with morphine. Following extinction training, a morphine drug prime reinstated the morphine place preference.
L A, Parker, R V, Mcdonald
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Preference and aversion for brain stimulations estimated by the conditioned place preference
Archives Internationales de Physiologie et de Biochimie, 1987Rats implanted with chronic electrode into the medial forebrain bundle at the level of the hypothalamus (which elicited self-stimulation behaviour) display conditioned place preference after repeated stimulations of this area; conversely rats implanted into the mesencephalic dorso-medial tegmentum (which elicited switch-off behaviour) present ...
P, De Witte, M, Gewiss
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Adenosine receptor agents and conditioned place preference
General Pharmacology: The Vascular System, 19971. The effects of different doses of the adenosine agonists N5-ethylcarboxamido-adenosine (NECA), R-isomer of N6-phenylisopropyladenosine (R-PIA), and N6-cyclohexyladenosine (CHA) or of the antagonists theophylline and 8-phenyltheophylline (8-PT) on conditioned place preference (CPP) have been studied. 2.
M R, Zarrindast, A A, Moghadamnia
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Psychopharmacology, 1998
Four experiments examined the effect of naloxone pretreatment on the expression and extinction of ethanol-induced conditioned place preference (experiments 1, 2, 4) or conditioned place aversion (experiments 1, 3). DBA/2 J mice received four pairings of a distinctive tactile (floor) stimulus (CS) with injection of ethanol (2 g/kg) given either ...
Christopher L Cunningham +1 more
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Four experiments examined the effect of naloxone pretreatment on the expression and extinction of ethanol-induced conditioned place preference (experiments 1, 2, 4) or conditioned place aversion (experiments 1, 3). DBA/2 J mice received four pairings of a distinctive tactile (floor) stimulus (CS) with injection of ethanol (2 g/kg) given either ...
Christopher L Cunningham +1 more
exaly +3 more sources
Opioidergic modulation of cocaine conditioned place preferences
Life Sciences, 1992Recent studies have begun to assess the utility of opioid agonists and antagonists for the treatment of cocaine addiction. The present studies assess the effects of naltrexone or methadone on cocaine's reinforcing properties using the conditioned place preference (CPP) test.
E J, Bilsky +3 more
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Methadone produces conditioned place preference in the rat
Pharmacology Biochemistry and Behavior, 1996The appetitive properties of methadone were investigated using the conditioned place preference paradigm. Male Sprague-Dawley rats received conditioned place preference training for a 6-day period. The apparatus consisted of two chambers with distinctive visual and tactile cues, separated by removable doors.
R E, Steinpreis +2 more
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