Results 91 to 100 of about 514,614 (257)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Timing in trace conditioning of the nictitating membrane response of the rabbit (Oryctolagus cuniculus) : scalar, nonscalar, and adaptive features [PDF]

, 2010
Using interstimulus intervals (ISIs) of 125, 250, and 500 msec in trace conditioning of the rabbit nictitating membrane response, the offset times and durations of conditioned responses (CRs) were collected along with onset and peak latencies.
Richard S. Sutton, Sutton, Richard S., Elliot A. Ludvig, Kehoe, E. James, E. James Kehoe, Ludvig, Elliot Andrew   +5 more
core   +1 more source

Changes in hair cortisol and oxytocin independently associate with positive and negative psychological states in female soccer players

Frontiers in Sports and Active Living
IntroductionThis study examined changes in hair cortisol concentration (HCC) and hair oxytocin concentration (HOC) in female athletes and aimed to clarify their relationships with training load, daily life stressors, and mental health indicators ...
Nodoka Ohara, Hana Kameo, Genta Ochi, Genta Ochi   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

External Load in High-Level Tennis Training: Influence of Game-Specific Drills in Junior and Professional Players Across Playing Situations

Applied Sciences
This study explored the influence of game-specific on-court drills on external load in junior and professional male tennis players. Using wearable inertial technology, a total of 345 drills performed during a training microcycle were analyzed.
Francisco José Penalva-Salmerón, Miguel Crespo, Rafael Martínez-Gallego, Jesús Ramón-Llin, José Francisco Guzmán   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Multi-isocentric volumetric arc-based total body irradiation: radiation dose impact on oncological outcomes in patients receiving allogeneic hematopoietic cell transplantation

Frontiers in Oncology
Background and purposeTotal body irradiation (TBI) is an important component of conditioning schedules. Data comparing different radiotherapy (RT) regimens in allogeneic hematopoietic cell transplantation (allo-HCT) remain limited.
Anna Romanowska, Joanna Kamińska, Alicja Sadowska-Klasa, Anita Prawdzik–Dampc, Renata Zaucha   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Comparative Effects of Repeated Linear Sprint and Change-of-Direction Speed Training on Performance, Perceived Exertion and Enjoyment in Youth Soccer Players

Sports
Youth soccer requires an integrated approach combining technical–tactical, physical, and psychological components to enhance performance and long-term engagement.
Okba Selmi, Mohamed Amine Rahmoune, Hamza Marzouki, Bilel Cherni, Anissa Bouassida, Antonella Muscella, Santo Marsigliante, Jolita Vveinhardt, Wafa Douzi   +8 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source