Results 101 to 110 of about 1,581,275 (287)

RANS Equations with Explicit Data-Driven Reynolds Stress Closure Can Be Ill-Conditioned

open access: yes, 2019
Reynolds-averaged Navier--Stokes (RANS) simulations with turbulence closure models continue to play important roles in industrial flow simulations. However, the commonly used linear eddy viscosity models are intrinsically unable to handle flows with non ...
Sun, Rui   +3 more
core   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Can I use a Panel? Panel Conditioning and Attrition Bias in Panel Surveys [PDF]

open access: yes
Over the past decades there has been an increasing use of panel surveys at the household or individual level, instead of using independent cross-sections.
Das, J.W.M.   +2 more
core   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Heart rate and time-motion analyses in top junior players during basketball matches

open access: yesActa Universitatis Palackianae Olomucensis. Gymnica, 2013
BACKGROUND: Basketball performance can be classified as an intermittent physical activity due to the changing situational game conditions and the number of intervening variables.
Karel Hůlka, Roman Cuberek, Jan Bělka
doaj  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

How much compliance is too much compliance: Is long-term ABA therapy abuse?

open access: yesCogent Psychology, 2019
This article discusses the prevalence of ASD with specific regard to the most ubiquitous current treatment, Applied Behavior Analysis (ABA). A discussion of some of the issues with the underlying theory of ABA in its current application is conducted ...
Aileen Herlinda Sandoval-Norton   +1 more
doaj   +1 more source

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