Results 81 to 90 of about 1,581,275 (287)
AIMS Neuroscience, 2015 A fundamental assumption of current hypotheses regarding hippocampal involvement in memory formation is that changes in synaptic connections between hippocampal neurons serve to encode information about recent events.
Eduardo Mercado III
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Initial conditioning of Polymer Eelectrolyte Membrane fuel cell by temperature and potential cycling
Acta Chimica Slovenica, 2014 Polymer electrolyte membrane fuel cells need initial conditioning, activation or break-in the first time they are operated after being assembled. During this period performance of the fuel cell improves until it reaches its nominal performance. The exact
Dario Bezmalinović +2 more
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Ignorance in the Relational Model [PDF]
, 2006 We hypothesize that an extension-with-conditioning of Dempster-Shafer theory is suitable for encoding uncertainty and ignorance in the Relational Model.
Fokkinga, Maarten M.
core +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Sex differences in fear conditioning in posttraumatic stress disorder
European Journal of Psychotraumatology, 2012 Rationale/statement of the problem: Women are twice as likely as men to develop Posttraumatic stress disorder (PTSD). Abnormal acquisition of conditioned fear has been suggested as a mechanism for the development of PTSD.
Sabra S. Inslicht +6 more
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Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Paul Eelen: Reflections on Life and Work
Psychologica Belgica, 2018 This manuscript is part of a special issue to commemorate professor Paul Eelen, who passed away on August 21, 2016. Paul was a clinically oriented scientist, for whom learning principles (Pavlovian or operant) were more than salivary responses and lever ...
Dirk Hermans +8 more
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