Results 111 to 120 of about 120,420 (290)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A responsive integrated dry route for uranium hexafluoride conversion using machine intelligence
Energy Conversion and Management: XA modification of the integrated dry route (IDR) process for uranium conversion in nuclear fuel fabrication to render it responsive to react and adapt to changes in measured variables is described.
Manuel Bandala +15 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A Class of Arbitrarily Ill Conditioned Floating-Point Matrices [PDF]
SIAM Journal on Matrix Analysis and Applications, 1991 Let IF be floating-point number system with basis beta > 2 and an exponent range consisting at least of the exponents 1 and 2. A class of arbitrarily ill-conditioned matrices is described the coefficients of which are elements of IF. Due to the very rapidly increasing sensitivity of those matrices they might be regarded as "almost" ill-posed ...
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Formally Verified Conditions for Regularity of Interval Matrices [PDF]
, 2010 We propose a formal study of interval analysis that concentrates on theoretical aspects rather than on computational ones. In particular we are interested in conditions for regularity of interval matrices. An interval matrix is called regular if all scalar matrices included in the interval matrix have non-null determinant and it is called singular ...
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A Survey of Condition Number Estimation for Triangular Matrices [PDF]
SIAM Review, 1987 Some methods of estimating the condition number of a triangular matrix without actually computing its inverse or singular value decomposition are discussed. They consist of one or two steps of inverse iteration with an appropriately chosen starting vector, possibly applying a matrix whose condition majorizes the actual one.
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Podium, 2021 The importance and transcendence of each variable that influences flexibility training in gymnasts, evaluated by specialists, could be modeled prospectively to consider medium and long term decisions related to the training management process.
Ninfa Julissa Gálvez Eras
doaj