Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Reciprocity & Responsibility: Conducting Research via Mentorship and Partnership
, 2021 Conducting Creative Research presentation "Reciprocity & Responsibility: Conducting Research via Mentorship and Partnership," a conversation between Cecily Nicholson and Syrus Marcus Ware on October 15, 2021.
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
User Needs Assessment for the Adaptive Management Portal
, 2002 Consultants, and Computer Science backgrounds employed to gather user needs/ requirements for a Forestry Portal. The paper will first inform the reader on the background and objectives of the Forestry Portal Project and then discuss the lessons learned ...
Dg Submission Submission
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JMIR Research ProtocolsBackgroundBedside ultrasonography, also known as point-of-care ultrasound (PoCUS), is a promising technological tool that enhances clinical assessment, enriching diagnostic capabilities and clinical reasoning.
Fernanda Raphael Escobar Gimenes +8 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Health promotion needs assessment in Argyll and Bute
, 1994 This report is the result of a qualitative health promotion needs assessment in Argyl l and Bute. The concept of community participation in needs assessment has a firm grounding in Health Promotion practice, It has long been recognised that Health ...
Gray, Susan M
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Conducting a needs assessment survey and user requirement study for an electronic phytosanitary certification system : the experience of Malaysia [PDF]
, 2016 This guidance document seeks to draw general principles and lessons learnt from the implementation of the electronic phytosanitary certification system in Malaysia.
UN.ESCAP +1 more
core +1 more source
Health needs assessment of lesbian, gay, bisexual, transgender and non-binary people: findings related to the Covid-19 pandemic [PDF]
, 2020 In recognition of the gaps in knowledge about the health and wellbeing of LGBT+ groups, NHS Greater Glasgow & Clyde (NHSGGC) and NHS Lothian commissioned a comprehensive health needs assessment of LGBT+ people in both health board areas.
Leven, Traci
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Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source