Results 61 to 70 of about 133,001,789 (236)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Health needs assessment of lesbian, gay, bisexual, transgender and non-binary people: literature review [PDF]
, 2019 We are delighted to present the report of our literature review which forms the first part of our Health Needs Assessment of people who are lesbian, gay, bisexual, transgender, or non-binary (LGBT+).
Leven, Traci
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Conducting a Needs Assessment for the Implementation of Computer Based Training within a Corporate Environment [PDF]
, 2007 ix, 69 p. This paper was completed as part of the final research component in the University of Oregon Applied Information Management Master's Degree Program [see htpp://aim.uoregon.edu].Computer Based Training (CBT) can fail to deliver real business ...
Maldonado, Brandon
core +1 more source
International Journal of Applied Earth Observations and GeoinformationAttribution of forest disturbance types using satellite remote sensing is practicable and several methods have been developed to automate the procedure. However, limited by commonly used data and the methodology, achieving accurate and rapid attribution ...
Zhe Li, Tetsuji Ota, Nobuya Mizoue
doaj +1 more source
ESSENTIALS OF SOCIAL MEDICINE AND MEDICAL ETHICS: A BOOK REVIEW [PDF]
SanamedBOOK DETAILS First Book: Essentials of Social Medicine and Medical Ethics © First Edition, 2016 Editor: Lydia Katrova Publisher: Lydia Katrova-Leading Technologies in Dentistry, Sofia, Bulgaria ISBN Number: 978-954-90363-5-0 Second ...
Dencheva Maria
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Health needs assessment of lesbian, gay, bisexual, transgender and non-binary people
, 2020 We are delighted to present the first two reports of our Health Needs Assessment of people who are lesbian, gay, bisexual, transgender, or non-binary (LGBT+). This needs assessment has been undertaken by both of our health boards working in partnership,
McCallum, Alison +2 more
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Prison health in NHS Greater Glasgow & Clyde a health needs assessment [PDF]
, 2012 The aim of this Health Needs Assessment (HNA) was to provide a systematic baseline assessment of the health and health care needs of prisoners in NHS Greater Glasgow and Clyde (NHSGGC) and to identify gaps in the current service provision to inform ...
Knifton, Lee +2 more
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