Results 91 to 100 of about 413,327 (305)

Hot bubbles of planetary nebulae with hydrogen-deficient winds - II. Analytical approximations with application to BD+30$^\circ$3639

, 2018
The first high-resolution X-ray spectroscopy of the planetary nebula BD+30$^\circ$3639 allowed to study X-ray emitting "hot bubbles" (HBs) of planetary nebulae in unprecedented detail.
Heller, René, Jacob, Ralf, Schönberner, Detlef, Steffen, Matthias   +3 more
core   +1 more source

Precise modelling of switching and conduction losses in cascaded h-bridge multilevel inverters [PDF]

, 2014
Nowadays, voltage source multilevel inverters are being used extensively in industry due to its many advantages, compared to conventional two level inverters, such as higher output voltage at low switching frequency, low voltage stress(dv/dt), lower ...
Alamri, B, Darwish, M
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Sensorineural Hearing Loss in Otosclerosis Surgery

Acta Medica
Background: During otosclerosis surgery, operative trauma can lead to decreased bone conduction. Aims: The study aims to observe the bone conduction changes after otosclerosis operations and analyse possible factors affecting the postoperative decrease ...
Kristýna Néma, Viktor Chrobok, Jan Mejzlík, Vladimír Pavlík, Lukáš Školoudík   +4 more
doaj   +1 more source

Sistem Pemanfaatan Energi Surya untuk Pemanas Air dengan Menggunakan Kolektor Palungan [PDF]

, 2014
A research has been conducted on Solar Energy Utilization System for Water Heater using Trough Collector. This research was carried out using an experimental method by putting in place an opened trough collector that exposed to sunlight.
Fatmawati, F. (Fatmawati), Ginting, M. (Maksi), Tambunan, W. (Walfred)   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Regression equation analysis enhances detection of conduction slowing beyond axonal loss in diabetic neuropathy

Heliyon
Objectives: To evaluate the utility of regression analysis in the assessment of conduction slowing in diabetic distal symmetrical polyneuropathy (DSP) and in identifying superimposed demyelination beyond fiber loss.
Nizar Souayah, Zhao Zhong Chong, Tejas Patel, Abu Nasar, Ankit Pahwa, Howard W Sander   +5 more
doaj   +1 more source

The Launching of Cold Clouds by Galaxy Outflows II: The Role of Thermal Conduction

, 2016
We explore the impact of electron thermal conduction on the evolution of radiatively-cooled cold clouds embedded in flows of hot and fast material, as occur in outflowing galaxies.
Brüggen, Marcus, Scannapieco, Evan
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source