Results 91 to 100 of about 415,480 (301)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Decay Rates of The Solution to the Cauchy Problem of the Type III Timoshenko Model Without Any Mechanical Damping

Demonstratio Mathematica, 2015
In this paper, we study the asymptotic behavior of the solutions of the one-dimensional Cauchy problem in Timoshenko system with thermal effect. The heat conduction is given by the type III theory of Green and Naghdi.
Said-Houari Belkacem
doaj   +1 more source

Hot bubbles of planetary nebulae with hydrogen-deficient winds I. Heat conduction in a chemically stratified plasma

, 2015
Heat conduction has been found a plausible solution to explain discrepancies between expected and measured temperatures in hot bubbles of planetary nebulae (PNe).
Rühling, Ute, Sandin, Christer, Schönberner, Detlef, Steffen, Matthias   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Sensorineural Hearing Loss in Otosclerosis Surgery

Acta Medica
Background: During otosclerosis surgery, operative trauma can lead to decreased bone conduction. Aims: The study aims to observe the bone conduction changes after otosclerosis operations and analyse possible factors affecting the postoperative decrease ...
Kristýna Néma, Viktor Chrobok, Jan Mejzlík, Vladimír Pavlík, Lukáš Školoudík   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Band engineering in dilute nitride and bismide semiconductor lasers

, 2012
Highly mismatched semiconductor alloys such as GaNAs and GaBiAs have several novel electronic properties, including a rapid reduction in energy gap with increasing x and also, for GaBiAs, a strong increase in spin orbit- splitting energy with increasing ...
Broderick, CA, Broderick, CA, O'Reilly, EP, O'Reilly, EP, Sweeney, SJ, Usman, M   +5 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Evaporation and condensation of spherical interstellar clouds. Self-consistent models with saturated heat conduction and cooling

, 2007
Shortened version: The fate of IS clouds embedded in a hot tenuous medium depends on whether the clouds suffer from evaporation or whether material condensates onto them.
Begelman, Brüns, Brüns, Böhringer, Campbell, Chevalier, Cowie, Crank, Dalgarno, Dalton, Danly, de Jong, de Jong, Field, G. Hensler, Graham, Heyer, Juncosa, Keenan, Khan, Koyama, Manheimer, Matte, McKee, McKee, Morse, Murray, Normandeau, Penston, Pietz, Raymond, Rozyczka, Samland, Slavin, Taylor, van Leer, Vieser, W. Vieser, Wakker, Wakker, Yorke   +40 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source