Results 101 to 110 of about 80,117 (291)

Design and Kinematics Performance Analysis of an Equivalent 3-PzPxS Parallel Mechanism

open access: yesJixie chuandong, 2020
In order to meet the requirements of the configuration innovation of the multi-axis linkage processing platform, a new type of 2R1T 3-PzPxS parallel mechanism is synthesized, which contains a planar pantograph structure unit in the branching chain.
Yeping Lü   +4 more
doaj  

Robust Control for High-Speed Visual Servoing Applications

open access: yesInternational Journal of Advanced Robotic Systems, 2007
This paper presents a new control scheme for visual servoing applications. The approach employs quadratic optimization, and explicitly handles both joint position, velocity and acceleration limits.
Lars-Peter Ellekilde   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

From singularities to graphs

open access: yes, 2018
In this paper I analyze the problems which led to the introduction of graphs as tools for studying surface singularities. I explain how such graphs were initially only described using words, but that several questions made it necessary to draw them ...
Popescu-Pampu, Patrick
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Configurations and singularity of hybrid mechanism [PDF]

open access: yesProceedings of the 2nd Annual International Conference on Electronics, Electrical Engineering and Information Science (EEEIS 2016), 2017
Mao-Yan He, Jian-Guo Luo
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Geodesic motion near self-gravitating scalar field configurations

open access: yesDiscrete and Continuous Models and Applied Computational Science, 2019
We study the geodesics motion of neutral test particles in the static spherically symmetric spacetimes of black holes and naked singularities supported by a selfgravitating real scalar field.
Ivan M. Potashov   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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