Results 61 to 70 of about 167,464,841 (288)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
In this work we consider the problem of classifying all configurations of singularities, both finite and infinite of quadratic differential systems, with respect to the geometric equivalence relation defined in [3].
Joan C. Artes +3 more
doaj
Material characteristics and input-field specifics limit controllability of nonlinear electromagnetic-field interactions. As these nonlinear interactions could be exploited to create strongly localized bright and dark waves, such as nonlinear surface ...
Saeid Asgarnezhad-Zorgabad +4 more
doaj +1 more source
On finite configurations in the spectra of singular measures
We establish various forms of the following certainty principle: a set $S \subset \mathbb{R}^{n}$ contains a given finite linear pattern, provided that $S$ is a support of the Fourier transform of a sufficiently singular probability measure on $\mathbb{R}^{n}$. As its main corollary, we provide new dimensional estimates for PDE- and Fourier-constrained
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
On dynamically consistent Jacobian inverse for non-holonomic robotic systems
This paper presents the dynamically consistent Jacobian inverse for non-holonomic robotic system, and its application to solving the motion planning problem.
Ratajczak Joanna, Tchoń Krzysztof
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Euclidean Field Theory and Singular Classical Field Configurations [PDF]
11 pages ...
openaire +3 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

