Results 71 to 80 of about 3,227 (267)

Verification and Generation of Safe Straight Paths for a 4-DOF Spherical Manipulator

Tikrit Journal of Engineering Sciences, 2011
Sometimes in a manufacturing environment, a robotic arm is wanted to move in a straight path such as welding, painting and assembling. This straight path causes the manipulator to actuate all or most of its joints in the same time to track the path ...
Rawand Ehsan J.T
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Experimental identification of topological defects in 2D colloidal glass

Nature Communications
Topological defects are singularities within a field that cannot be removed by continuous transformations. The definition of these irregularities requires an ordered reference configuration, calling into question whether they exist in disordered ...
Vinay Vaibhav, Arabinda Bera, Amelia C. Y. Liu, Matteo Baggioli, Peter Keim, Alessio Zaccone   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Codimension in planar polynomial differential systems

Electronic Journal of Differential Equations
The topological classification of large families of polynomial differential systems remains an extremely difficult problem. Even for the simplest nonlinear case, the quadratic systems, this problem is still open.
Joan C. Artes, Jaume Llibre, Dana Schlomiuk, Nicolae Vulpe   +3 more
doaj  

Supersymmetric smooth distributions of M2-branes as AdS solitons

Journal of High Energy Physics
We show that the singularities of certain distributions of M2-branes can be removed by adding a Wilson loop around a compact direction along the brane.
A. Anabalón, D. Astefanesei, A. Gallerati, J. Oliva   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Design and Kinematics Performance Analysis of an Equivalent 3-P_zP_xS Parallel Mechanism

Jixie chuandong, 2020
In order to meet the requirements of the configuration innovation of the multi-axis linkage processing platform， a new type of 2R1T 3-PzPxS parallel mechanism is synthesized， which contains a planar pantograph structure unit in the branching chain.
Yeping Lü, Yong Xu, Wei Liang Song, Zheng Liang, Yong Liu   +4 more
doaj  

Robust Control for High-Speed Visual Servoing Applications

International Journal of Advanced Robotic Systems, 2007
This paper presents a new control scheme for visual servoing applications. The approach employs quadratic optimization, and explicitly handles both joint position, velocity and acceleration limits.
Lars-Peter Ellekilde, Peter Favrholdt, Mads Paulin, Henrik Gordon Petersen   +3 more
doaj   +1 more source