Results 41 to 50 of about 155,906 (299)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
OEDGE modeling of far-SOL tungsten impurity sources and screening in WEST
Nuclear Materials and Energy, 2022 The plasma background and impurity transport in the scrape-off layer (SOL) of the WEST tokamak are modeled for three discharges over a Psep power scan ranging between 1.5 and 2.35 MW. An extended modeling grid is used to investigate far-SOL sourcing from
J.B. Maeker +10 more
doaj
Brazilian Journal of Physics, 2019 16 pages, no ...
R. L. P. G. Amaral +3 more
openaire +2 more sources
Nature Communications, 2022 AbstractThe growth of crystals confined in porous or cellular materials is ubiquitous in Nature and forms the basis of many industrial processes. Confinement affects the formation of biominerals in living organisms, of minerals in the Earth’s crust and of salt crystals damaging porous limestone monuments, and is also used to control the growth of ...
Felix Kohler +2 more
openaire +5 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Understanding the spectrum during the tearing mode locking by rotating RMP in J-TEXT
AIP Advances, 2022 The rotating resonant magnetic perturbation (RMP) could lock the tearing mode (TM) and prevent disruption. It is found that the TM instantaneous frequency oscillates during TM locking on the RMP.
Da Li +18 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
The confining trailing string [PDF]
Journal of High Energy Physics, 2014 We extend the holographic trailing string picture of a heavy quark to the case of a bulk geometry dual to a confining gauge theory. We compute the classical trailing confining string solution for a static as well as a uniformly moving quark. The trailing string is infinitely extended and approaches a confining horizon, situated at a critical value of ...
L. Mazzanti +4 more
openaire +7 more sources
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
IET Electric Power Applications, 2022 With the development of modern tokamak devices, the magnetic interference problem has become increasingly serious. On considering the International Thermonuclear Experimental Reactor (ITER), for example, the stray magnetic field around the tokamak device
Boliang Zhu +5 more
doaj +1 more source