Results 181 to 190 of about 461,964 (264)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Task-sharing anaesthesia in conflict zones: a cross-sectional study of safety gaps and systemic failures in Wad Medani, Sudan. [PDF]

BMC Health Serv Res
Mohamed A, Taha SM, Hassan YM, Bashir M, Alphonsus C.   +4 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Commercial and Corporate Provision of Healthcare, Capitalism and the State. [PDF]

Sociol Health Illn
Fox NJ.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Their voices matter: assessing patients' experience with healthcare quality in a war-torn country. [PDF]

Confl Health
Elsharif SAM, Altahir AM, Mohammed AY, Zakaria N, Mohammed AKA, Shannan A, Abdelhaleem O, Bashir R, Hassan SS, Elhassan S, Abdelraheem EMH, Mohamed AB, Osman M.   +12 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Leveraging community insights and navigating logistical challenges: a case study of the 2024 polio vaccination campaign in Gaza, State of Palestine. [PDF]

BMJ Glob Health
Dwyer H, Hasan MR, Abeshu M, Tsega A, Farrukh S, Kadandale S, Lainez J, Galvin M, Gough J, Higgins E, Wishah I, Onitolo E, Seyam N, Ibrahim AR, Young H, Said S, Achari AP, Goundara AM, Girma T, Lauwerier S, Beckmann N, Palmer J, Enria L, McIntosh R.   +23 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

White Coats and Billboards: An Ethical Analysis of Surgeons' Attitudes towards Physicians' Advertisements in a Middle-Income Setting. [PDF]

J Adv Med Educ Prof
Masoudiyekta L, Rezaeiamjad P, Asghari F, Shamsi-Gooshki E, Ahmadi A, Parsapour A.   +5 more
europepmc   +1 more source