Results 191 to 200 of about 150,034 (233)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

The Eurostack of digital health cybersecurity. [PDF]

Front Digit Health
Brightwell C, Carboni C, Halpern O.
europepmc   +1 more source

A comparative review of health care and occupational health systems across selected Asian countries. [PDF]

Environ Occup Health Pract
Indriyati LH, Eitoku M, J-P NA, Tamura T, Suganuma N.   +4 more
europepmc   +1 more source

Risk Calibration: Divergent Interpretations of Risk Assessment in Norway's Early COVID-19 Response. [PDF]

Risk Anal
Karlsen AR.
europepmc   +1 more source

Low-titer group O whole blood transfusion in high-intensity war: an insight from Ukraine. [PDF]

Crit Care
Lurin I, Mikheiev I, Kuziv R, Machuskyi S, Dinets A.   +4 more
europepmc   +1 more source

Healthcare Leadership in Resource-Limited Settings: Reimagining Public Hospital Governance in Somalia. [PDF]

J Healthc Leadersh
Ali AS, Ahmed MM.
europepmc   +1 more source

State-Funded Health Insurance Expansion for Noncitizen Immigrants and Hospital Uncompensated Care.

JAMA Netw Open
Martinez-Cardoso A, Yu B, Nayak A, Kaestner R, Bustamante AV.   +4 more
europepmc   +1 more source

Health System Policies Following State Abortion Restrictions in the US.

JAMA Netw Open
Shadow L, Ray A, Schroeder B, Bernard C, Chen C, Gershengorn HB, Ashana DC.   +6 more
europepmc   +1 more source