Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Conflicts and Collisions With an Endangered Carnivore: Landscape Drivers and Spatial Risk Pattern. [PDF]
Prat-Guitart M +3 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Distributed Event-Driven Bayesian Search for Multi-UAV Systems with Spatially Correlated Targets. [PDF]
Niu D, Yi P, Hong Y.
europepmc +1 more source
Antimicrobial-laden PerOssal beads display in vitro inhibition and killing of extensively drug-resistant Gram-negative bacteria associated with conflict wounds in Ukraine. [PDF]
Claireaux HA +8 more
europepmc +1 more source
The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security. [PDF]
Olwit G +4 more
europepmc +1 more source
Changes in ethics and transparency reporting in dental journal articles between 2021 and 2025: a full-text cross-journal analysis. [PDF]
Better H +4 more
europepmc +1 more source
Sharing conspiracy theories and staying in power: How leaders' false theories influence leadership perception. [PDF]
Cao S, van Prooijen JW, van Vugt M.
europepmc +1 more source
Alert-associated cardiovascular events in Gulf civilian populations: emerging risks and surveillance opportunities. [PDF]
Iftikhar H.
europepmc +1 more source

