Results 101 to 110 of about 1,777,402 (303)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Theorizing Mediation: Lessons Learned from Legal Anthropology
Utrecht Law Review, 2016 Since the 1990s, there has been an increasing interest in mediation in the Netherlands, as part of a set of ‘alternative dispute resolution’ methods.
Marc Simon Thomas
doaj +1 more source
What Can Anthropologists Do?: Applied Anthropology in a Conflict-Ridden World
, 2019 This work examines the role of anthropology in conflict, post-conflict studies, and conflict resolution. Present research has asserted that Anthropology as a discipline must move forward with greater involvement in domestic and international conflict ...
Dorshimer, Emma G.
core
Contemporary Conflict Resolution and Islamic Conflict Resolution: Similarity and Differentiation on the Theoretical Level [PDF]
, 2014 The critiques towards Cosmopolitan conflict resolution theory that it cannot be applied universally because it is incompatible with the characteristics of the conflict in the other part of the world beyond Western significantly influence the field ...
Sabban, N. (Nabilla)
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Root Problem and Conflict Resolution of Fisheries in Sea Waters of South Kalimantan [PDF]
, 2012 Conflict of fisheries (capture fisheries cases of purse seine) in the sea waters of Kotabaru South Kalimantan, require serious attention. The government has made some efforts to overcome it but not yet effective.
usmilyansari, R. (R)
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Automating the conflict resolution process [PDF]
The purpose is to initiate a discussion of how the conflict resolution process at the Network Control Center can be made more efficient. Described here are how resource conflicts are currently resolved as well as the impacts of automating conflict ...
Wike, Jeffrey S.
core +1 more source