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Ultrasensitive Chemical Detection Using Integrating Cavity-Enhanced Raman Spectroscopy. [PDF]
Moore TZ +5 more
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A new paradigm in dermatopharmacokinetics – Confocal Raman spectroscopy
International Journal of Pharmaceutics, 2013Confocal Raman spectroscopy (CRS) is a novel approach which has been used to determine stratum corneum thickness and to profile endogenous skin components. However, the utility of this technique for probing drug disposition in vivo has not been explored to date.
Majella Lane +2 more
exaly +3 more sources
Imaging of the Ferroelectric Domain Structures by Confocal Raman Spectroscopy
Ferroelectrics, 2011Confocal Raman spectroscopy was performed as an archetype imaging method to study the ferroelectric domain structure of periodically poled lithium niobate. More precisely, the linkage out of spatial resolution and spectral information proved itself as very useful.
Wolf Gero Schmidt, Simone Sanna
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Confocal Raman Spectroscopy of Whole Hairs
Applied Spectroscopy, 2013This paper describes the application of Raman spectroscopy to whole hair fibers. Previously this has proved difficult because the hairs are relatively opaque, and spatial resolution diminishes with depth because of the change in refractive index. A solution is to couple confocal Raman with multivariate curve resolution (MCR) data analysis, which ...
Paul D A, Pudney +5 more
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In Vivo Confocal Raman Spectroscopy of the Human Cornea
Cornea, 1999To investigate the feasibility of a confocal Raman spectroscopic technique for the noninvasive assessment of corneal hydration in vivo in two legally blind subjects.A laser beam (632.8 nm; 15 mJ) was maintained on the cornea by using a microscope objective lens (x25 magnification, NA = 0.5, f = 10 mm) both for focusing the incident light as well as ...
N J, Bauer, F, Hendrikse, W F, March
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On optical depth profiling using confocal Raman spectroscopy
Analytical and Bioanalytical Chemistry, 2009Until 2006 the performance of confocal Raman spectroscopy depth profiling was typically described and modeled through the application of geometrical optics, including refraction at the surface, to explain the degree of resolution and the precise form of the depth profile obtained from transparent and semicrystalline materials.
Freebody, N. A. +2 more
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Dual-Axes Confocal Microlens for Raman Spectroscopy
2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems, 2009This paper presents a novel dual-axes scanning microlens for in vivo near infrared (NIR) Raman spectroscopy. In vivo Raman spectra of fibrosarcoma tumor skin and normal mouse skin measured from the microlens are reported. Out-of-plane (Z-axis) and transverse (X-axis) actuations are demonstrated using electrostatic and electromagnetic forces ...
C.P.B. Siu, H. Wang, H. Zeng, M. Chiao
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Characterization of Graphene by Confocal Raman Spectroscopy
2018Confocal Raman spectroscopy has emerged as a key characterization technique in graphene research, as with this technique important material characteristics can be obtained locally and noninvasively. In this chapter, the fundamentals of the Raman spectrum of graphene are reviewed and the utilization of Raman spectroscopy for graphene characterization is
Christoph Neumann, Christoph Stampfer
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