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In vivo confocal Raman spectroscopy: The window into the skin

International Journal of Cosmetic Science
AbstractDevelopment of in vivo confocal Raman spectroscopy (ICRS) methodology over the last 20 years has enabled previously unavailable capability to acquire molecular concentration gradients across the stratum corneum (SC), at the micron level and in a clinical setting. Professor Tony Rawlings has been a driving force in SC research for over 30 years,
J. M. Crowther, P. J. Matts
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Stress Mapping by Confocal Raman Spectroscopy on Solar Cells and Modules

2018 IEEE 7th World Conference on Photovoltaic Energy Conversion (WCPEC) (A Joint Conference of 45th IEEE PVSC, 28th PVSEC & 34th EU PVSEC), 2018
In this work, we show the latest progress in the confocal micro-Raman spectroscopy for determination of stress within embedded solar cells. We present measurements proving that the module front glass has no influence on the stress measurement. We also present the first large area stress mapping on a quarter solar cell within a single-cell laminate.
Beinert, A. J.   +6 more
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Raman Spectroscopy and Confocal Raman Imaging in Mineralogy and Petrography

2010
Raman spectroscopy has long been used in geosciences and a wealth of data and publications are available. The majority of this information originates from point measurements using micro-Raman setups. With the application of confocal Raman imaging, additional analytical possibilities arise with respect to analyzing the three-dimensional spatial ...
Marc Fries, Andrew Steele
openaire   +1 more source

On Confocal Raman Spectroscopy of Semicrystalline Polymers: The Effect of Optical Scattering

Applied Spectroscopy, 2003
A series of semicrystalline polymers has been prepared through morphological control. Each of these has an identical refractive index but a different, well-defined, scattering behavior. From existing geometrical optical theories of confocal Raman spectroscopy, these materials should behave identically. Initially, the extent of scattering in each system
MacDonald, A. M.   +2 more
openaire   +3 more sources

In vivo Raman Confocal Spectroscopy in the Investigation of the Skin Barrier

2016
The epidermal barrier, predominantly attributed to the stratum corneum (SC), is the outermost part of our body that comprises multiple defensive functions against exogenous attacks and the loss of body substances, e.g. water. A novel investigative method, in vivo Raman confocal spectroscopy (RCS), is employed to study the composition of the epidermal ...
Razvigor, Darlenski, Joachim W, Fluhr
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Confocal Raman spectroscopy to trace lipstick with their smudges on different surfaces

Talanta, 2014
Lipsticks are very popular cosmetic products that can be transferred by contact to different surfaces, being important forensic evidence with an intricate analysis if they are found in a crime scene. This study evaluates the use of confocal Raman microscopy at 780 nm excitation wavelength for the nondestructive identification of 49 lipsticks of ...
Maria, López-López   +2 more
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Efficient Characterization for Protein Crystals Using Confocal Raman Spectroscopy

Applied Spectroscopy, 2007
Confocal Raman spectroscopy was applied to the characterization of various states emerging in the screening of protein crystallization. Four main characterized states, namely single crystals, microcrystals, precipitates, and clear drops without solid materials, appear in a droplet for crystallization; the first three states should be critically ...
Kohki, Noda   +4 more
openaire   +2 more sources

Surface Analysis Using Confocal Raman Micro-Spectroscopy

2002
Recent developments in instrumentation and the availability of several high quality commercial Raman microscopes have made Raman micro-spectroscopy an emerging tool for surface analysis. Specifically, confocal Raman micro-spectroscopy allows for near diffraction-limited spatial resolution, with the chemical and structural information of vibrational ...
C. Hyett   +3 more
openaire   +1 more source

Dual wavelength optical tweezers for confocal Raman spectroscopy

Optics Communications, 2005
We describe the use of dual optical tweezers to manipulate micron-size particles in and out of the focus of a confocal Raman microscope. One of the beams excites the Raman spectrum while the second tweezers improves the sensitivity of the technique and also allows for the manipulation of the environment of the trapped objects.
C.M. Creely, G.P. Singh, D. Petrov
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Confocal Raman spectroscopy applied to microemulsions and nanoemulsions

Current Opinion in Colloid & Interface Science
Raman spectroscopy is a light scattering technique in which a molecule scatters incident light at different wavelengths depending on the chemical structure of the analyte, from a high-intensity laser light source. The Raman scattered light is detected to create the Raman spectrum, which is unique to the chemical compounds present in the sample, acting ...
Fernandez, Cintia Judith   +4 more
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