Results 91 to 100 of about 1,518,966 (331)
The most tight conformation of the trefoil knot found by the SONO algorithm is presented.
A. Maritan +16 more
core +3 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Simulating the nanomechanical response of cyclooctatetraene molecules on a graphene device [PDF]
We investigate the atomic and electronic structures of cyclooctatetraene (COT) molecules on graphene and analyze their dependence on external gate voltage using first-principles calculations.
Cohen, Marvin L. +2 more
core +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The C–F bond as a conformational tool in organic and biological chemistry
Organofluorine compounds are widely used in many different applications, ranging from pharmaceuticals and agrochemicals to advanced materials and polymers.
Luke Hunter
doaj +1 more source
A quantitative trait locus (QTL) for increased loin muscularity (TM-QTL) has previously been identified in purebred Texel sheep. Crossbred lambs born out of Mule ewes mated to heterozygous Texel sires for the TM-QTL were evaluated for a range of carcass ...
E. Rius-Vilarrasa +7 more
doaj +1 more source
Mobility Measurements Probe Conformational Changes in Membrane Proteins due to Tension
The function of membrane-embedded proteins such as ion channels depends crucially on their conformation. We demonstrate how conformational changes in asymmetric membrane proteins may be inferred from measurements of their diffusion.
Morris, Richard G., Turner, Matthew S.
core +1 more source
Structure of Equilenin at 100 K: an estrone-related steroid [PDF]
The structure of the estrone-related steroid, Equilenin, C18H18O2 (systematic name 3-hy-droxy-13-methyl-11,12,13,14,15,16-hexa-hydro-cyclo-penta-[a]phen-anthren-17-one), has been determined at 100 K.
Frampton, Christopher S. +1 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Aperçu des techniques d'analyse conformationnelle des macromolécules biologiques [PDF]
Outline of conformational analysis techniques of the biological macromolecules. This paper presents a synthesis of thevarious methods of conformational analysis of biological macromolecules usually quoted in the literature.
Paquot M. +3 more
doaj

