Results 71 to 80 of about 206,324 (261)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Conformation-Dependent Photochemistry of 5-Halouracil-Containing DNA:  Stereospecific 2‘α-Hydroxylation of Deoxyribose in Z-form DNA

open access: yes, 2016
Conformation-Dependent Photochemistry of 5-Halouracil-Containing DNA:  Stereospecific 2‘α-Hydroxylation of Deoxyribose in Z-form ...
Isao Saito (2455927)   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Two tris(3,5-disubstituted phenyl)phosphines and their isostructural PV oxides

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
The crystal structures of tris(3,5-dimethylphenyl)phosphine (C24H27P), (I), tris(3,5-dimethylphenyl)phosphine oxide (C24H27OP), (II), tris(4-methoxy-3,5-dimethylphenyl)phosphine (C27H33O3P), (III), and tris(4-methoxy-3,5-dimethylphenyl)phosphine oxide ...
Nathan D. D. Hill, René T. Boeré
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Conformation of Circular DNA in Two Dimensions [PDF]

open access: yes, 2008
The conformation of circular DNA molecules of various lengths adsorbed in a 2D conformation on a mica surface is studied. The results confirm the conjecture that the critical exponent ν is topologically invariant and equal to the self-avoiding walk value
Witz, Guillaume   +7 more
core   +1 more source

Carcass characteristics of feedlot-finished Nellore heifers slaughtered at different weights

open access: yesActa Scientiarum: Animal Sciences, 2019
Carcass and meat characteristics of 48 Nellore heifers at 24 to 30 months of age, with an initial weight of 263.4 ± 13.9 kg, were evaluated. The experiment was set up as a completely randomized design with four treatments, which consisted of four ...
Pedro Leonardo de Paula Rezende   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Predicting beef carcass meat, fat and bone proportions from carcass conformation and fat scores or hindquarter dissection [PDF]

open access: yes, 2009
peer-reviewedEquations for predicting the meat, fat and bone proportions in beef carcasses using the European Union carcass classification scores for conformation and fatness, and hindquarter composition were developed and their accuracy was tested ...
Kenny, David A.   +5 more
core   +1 more source

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