Results 91 to 100 of about 206,324 (261)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Il professore immaginato e la valutazione come causa finale
Im@go. A Journal of the Social Imaginary, 2015 The article, by assuming as main theoretical framework some French and Italian critical perspectives concerning the critical analysis of the “evaluation” dispositive and its cognitive and social consequences, focuses on a questionnaire to be answered by ...
Mino Conte
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Development of a methodology to describe udder conformation in sows
Animal, 2016 The aim of this study was to develop a methodology to measure sow udder conformation to use in studying the correlation between udder traits and piglet survival, health and performance.
A. Balzani, H.J. Cordell, S.A. Edwards
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Justification and Conformity [PDF]
Journal of Economic Behavior & Organization, 2012 The need for justification is a widely observed social phenomenon and an important part of communication. This paper examines experimentally how pure justification pressure affects conformity behavior in economic environments. The evidence is consistent with justification pressure increasing sensitivity to norm deviations.
openaire +1 more source
Crystal structure of N-(propan-2-ylcarbamothioyl)benzamide
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the crystal structure of the title compound, C11H14N2OS, the six atoms of the central C2N2OS residue are coplanar (r.m.s. deviation = 0.002 Å), which facilitates the formation of an intramolecular N—H...O hydrogen bond, which closes an S(6) loop.
Jerry P. Jasinski +4 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2020 The synthesis and crystal structures of three new disubstituted [13]-macrodilactones, namely, trans-4,8-dimethyl-1,10-dioxacyclotridec-5-ene-2,9-dione, C13H20O4, I, cis-4-(4-bromophenyl)-13-methyl-1,10-dioxacyclotridec-5-ene-2,9-dione C18H21BrO4, II, and
Kelli M. Rutledge +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2019 Highly charged macromolecular ions exhibit various conformations in gas. Intramolecular charge-to-charge interaction induces a transformation from a globular structure into a stretched one.
Yoshio Otani (710252) +5 more
core +1 more source