Results 111 to 120 of about 1,518,966 (331)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Development of a methodology to describe udder conformation in sows

open access: yesAnimal, 2016
The aim of this study was to develop a methodology to measure sow udder conformation to use in studying the correlation between udder traits and piglet survival, health and performance.
A. Balzani, H.J. Cordell, S.A. Edwards
doaj   +1 more source

Design Equation: A Novel Approach to Heteropolymer Design

open access: yes, 1998
A novel approach to heteropolymer design is proposed. It is based on the criterion by Kurosky and Deutsch, with which the probability of a target conformation in a conformation space is maximized at low but finite temperature.
\uSali A.   +20 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Carcass characteristics of small and medium-frame Aberdeen Angus young steers=Características da carcaça de novilhos super jovens Aberdeen Angus de biótipos pequeno e médio [PDF]

open access: yesActa Scientiarum: Animal Sciences, 2012
Carcass characteristics of small and medium-frame Aberdeen Angus young steers, finished in feedlot and slaughtered with similar subcutaneous fat thickness are evaluated.
Lucas Braido Pereira   +5 more
doaj  

Crystal structure of N-(propan-2-ylcarbamothioyl)benzamide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the crystal structure of the title compound, C11H14N2OS, the six atoms of the central C2N2OS residue are coplanar (r.m.s. deviation = 0.002 Å), which facilitates the formation of an intramolecular N—H...O hydrogen bond, which closes an S(6) loop.
Jerry P. Jasinski   +4 more
doaj   +1 more source

Theory of Side-Chain Liquid Crystal Polymers: Bulk Behavior and Chain Conformation [PDF]

open access: yes, 2010
We study the thermodynamics and chain conformation of side-chain liquid crystal polymers (SCLCPs) in the bulk using the self-consistent-field approach and a new model to account for the coupling between the orientation of the side-chain liquid-crystal ...
Wang, Rui, Wang, Zhen-Gang
core  

Multiplexed analysis of chromosome conformation at vastly improved sensitivity

open access: yesNature Methods, 2015
Methods for analyzing chromosome conformation in mammalian cells are either low resolution or low throughput and are technically challenging. In next-generation (NG) Capture-C, we have redesigned the Capture-C method to achieve unprecedented levels of ...
James O. J. Davies   +6 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

cis-6-Methoxycarbonyl-2,10-dioxa-1-phosphabicyclo[4.4.0]decane 1-Oxide [PDF]

open access: yes, 1995
The crystal structure of the title compound, C9H1505P, is described. The molecule consists of two cis-fused six-membered rings, both in the chair conformation.
Bennett, Dennis W.   +4 more
core   +1 more source

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