Results 21 to 30 of about 3,678,372 (337)

Random Conformal Dynamical Systems [PDF]

Geometric and Functional Analysis, 2007
We consider random dynamical systems such as groups of conformal transformations with a probability measure, or transversaly conformal foliations with a Laplace operator along the leaves, in which case we consider the holonomy pseudo-group. We prove that either there exists a measure invariant under all the elements of the group (or the pseudo-group ...
Deroin, Bertrand, Kleptsyn, Victor A.
openaire   +5 more sources

Reconciling mediating and slaving roles of water in protein conformational dynamics. [PDF]

PLoS ONE, 2013
Proteins accomplish their physiological functions with remarkably organized dynamic transitions among a hierarchical network of conformational substates.
Li Zhao, Wenzhao Li, Pu Tian
doaj   +1 more source

Conformational Dynamics of Poly(T) Single-Stranded DNA at the Single-Molecule Level.

Journal of Physical Chemistry Letters, 2021
The conformational dynamics of single-stranded DNA (ss-DNA) are implicated in the mechanisms of several key biological processes such as DNA replication and damage repair and have been modeled with those of semiflexible or flexible polymer.
S. Kim, Tae-Hee Lee
semanticscholar   +1 more source

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

Science Advances, 2020
Structure of SARS-CoV-2 spike in complex with ACE2 reveals the mechanism of ACE2 induced spike conformational transitions. The recent outbreaks of SARS-CoV-2 pose a global health emergency.
Cong Xu, Yanxing Wang, Caixuan Liu, Chao Zhang, Wenyu Han, Xiaoyu Hong, Yifan Wang, Qin Hong, Shutian Wang, Qiaoyu Zhao, Yalei Wang, Yong Yang, Kaijian Chen, Wei Zheng, L. Kong, Fangfang Wang, Qinyu Zuo, Zhong Huang, Y. Cong   +18 more
semanticscholar   +1 more source

Nonlinearity of Mechanochemical Motions in Motor Proteins [PDF]

, 2010
The assumption of linear response of protein molecules to thermal noise or structural perturbations, such as ligand binding or detachment, is broadly used in the studies of protein dynamics.
A Cressman, A Kitao, Alexander S. Mikhailov, AN Zaikin, AR Atilgan, AT Winfree, B Brooks, B Brooks, BJ Foth, C Chennubhotla, F Piazza, F Tama, F Tama, I Bahar, J-L Liao, JR Sellers, K Hayashi, K Hinsen, L Yang, LD Landau, M Gerstein, M Ikeguchi, M Iwaki, M Kikkawa, M Kikkawa, M Levitt, M Tomishige, MM Tirion, N Gō, N Hirokawa, N Koga, O Miyashita, P Doruker, PD Coureux, PD Coureux, R Nitta, T Haliloglu, Toshio Yanagida, W Zheng, Willy Wriggers, Y Togashi, Yuichi Togashi   +41 more
core   +14 more sources

Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy

Molecules, 2022
Elucidation of physicochemical mechanisms of enzymatic processes is one of the main tasks of modern biology. High efficiency and selectivity of enzymatic catalysis are mostly ensured by conformational dynamics of enzymes and substrates.
Lyubov Yu. Kanazhevskaya, Denis A. Smyshliaev, Nadezhda A. Timofeyeva, Alexander A. Ishchenko, Murat Saparbaev, Nikita A. Kuznetsov, Olga S. Fedorova   +6 more
doaj   +1 more source

A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family.

PLoS Computational Biology, 2009
Conformational ensembles are increasingly recognized as a useful representation to describe fundamental relationships between protein structure, dynamics and function.
Gregory D Friedland, Nils-Alexander Lakomek, Christian Griesinger, Jens Meiler, Tanja Kortemme   +4 more
doaj   +1 more source

Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA. [PDF]

PLoS Computational Biology, 2014
Protein-DNA recognition is a central biological process that governs the life of cells. A protein will often undergo a conformational transition to form the functional complex with its target DNA.
Xiakun Chu, Fei Liu, Brian A Maxwell, Yong Wang, Zucai Suo, Haijun Wang, Wei Han, Jin Wang   +7 more
doaj   +1 more source

Conformal chiral dynamics [PDF]

Physical Review D, 2009
We investigate the chiral dynamics of gauge theories developing an infrared stable fixed point. We determine the dependence of the bilinear fermion condensate on the underlying fermion mass and its anomalous dimension. We introduce the instanton contributions and investigate how they affect the dynamics near the fixed point. We generalize the Gell-Mann
openaire   +4 more sources

Pressure, motion, and conformational entropy in molecular recognition by proteins

Biophysical Reports, 2023
The thermodynamics of molecular recognition by proteins is a central determinant of complex biochemistry. For over a half-century, detailed cryogenic structures have provided deep insight into the energetic contributions to ligand binding by proteins ...
José A. Caro, Kathleen G. Valentine, Taylor R. Cole, A. Joshua Wand   +3 more
doaj   +1 more source