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Congenital hyperinsulinism

open access: yesMedicina, 2014
Hyperinsulinism is the most common cause of hypoglycemia in infants. In many cases conservative treatment is not effective and surgical intervention is required.
Indrė Petraitienė   +6 more
doaj   +4 more sources

Nifedipine in Congenital Hyperinsulinism - A Case Report. [PDF]

open access: yesJournal of Clinical Research in Pediatric Endocrinology, 2016
PublishedJournal ArticleThis is the final version of the article. Available from Galenos Yayınevi via the DOI in this record.Congenital hyperinsulinism (CHI) is the commonest cause of persistent hypoglycemia in neonates.
Basak, D   +4 more
core   +5 more sources

Neonatal congenital hyperinsulinism in Indonesia

open access: yesJournal of Pediatric Surgery Case Reports, 2021
Introduction: Congenital hyperinsulinism (CHI) is resulted from dysregulated insulin secretion from hyperplastic and hyperactive but apparently normally structured β-cells islet.
I.Made Arimbawa   +5 more
doaj   +3 more sources

Techniques in Pediatric Surgery: Congenital Hyperinsulinism [PDF]

open access: yesHormone Research in Paediatrics, 2011
For surgery in congenital hyperinsulinism (CHI), a distinct surgical strategy and technique is required for focal, diffuse and atypical CHI. In focal CHI, a confined, localized and parenchyma-sparing resection which is guided by the PET-CT is always ...
Barthlen, Winfried   +2 more
core   +5 more sources

Congenital hyperinsulinism

open access: hybridEarly Human Development, 2010
Congenital hyperinsulinism (CHI or HI) is a condition leading to recurrent hypoglycemia due to an inappropriate insulin secretion by the pancreatic islet beta cells. HI has two main characteristics: a high glucose requirement to correct hypoglycemia and a responsiveness of hypoglycemia to exogenous glucagon.
Maria Melikian
openalex   +3 more sources

New approaches to screening and management of neonatal hypoglycemia based on improved understanding of the molecular mechanism of hypoglycemia

open access: yesFrontiers in Pediatrics, 2023
For the past 70 years, controversy about hypoglycemia in newborn infants has focused on a numerical “definition of neonatal hypoglycemia”, without regard to its mechanism.
Charles A. Stanley   +5 more
doaj   +1 more source

Congenital hyperinsulinism - surgical treatment and complications [PDF]

open access: green, 2011
{"references": ["Hussain K. Congenital hyperinsulinism. Seminars in Fetal & Neonatal Medicine (2005) 10, 369.", "De Lonlay-Debeney P, Poggi-Travert F, Fournet JC, Sempoux C, Vici CD, Brunelle F, Touati G, Rahier J, Junien C, Nihoul-Fekete C, Robert JJ, Saudubray JM. Clinical features of 52 neonates with hyperinsulinism. N Engl J Med. 1999. 340:1169-
Marko Bogović   +5 more
openalex   +5 more sources

Congenital Hyperinsulinism

open access: yesNeoReviews, 2021
Hyperinsulinemic hypoglycemia (HH) is fairly common in neonates, particularly those born to diabetic mothers and those who are either large or small for gestational age. Immediate management of the disease focuses on achieving normoglycemia through frequent high-calorie feedings and/or intravenous glucose administration.
Sugandha Arya   +3 more
openaire   +5 more sources

Modern therapeutic aspects in two cases of congenital hyperinsulinism [PDF]

open access: yesRomanian Journal of Pediatrics, 2020
In this article we will present the therapeutic and clinical aspects found in the case of two pediatric patients diagnosed with congenital hyperinsulinism.
Cristian Minulescu, Dana Spirea
doaj   +1 more source

Congenital Hyperinsulinism: Current Laboratory-Based Approaches to the Genetic Diagnosis of a Heterogeneous Disease

open access: yesFrontiers in Endocrinology, 2022
Congenital hyperinsulinism is characterised by the inappropriate release of insulin during hypoglycaemia. This potentially life-threatening disorder can occur in isolation, or present as a feature of syndromic disease.
Thomas I. Hewat   +2 more
doaj   +1 more source

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