Results 31 to 40 of about 1,403 (143)
Медицинский совет, 2022 Introduction. Congenital hyperinsulinism is a rare group of genetic disorders resulting in persistent hypoglycemia which can lead to delay of neurodevelopment.Aim.
I. L. Nikitina +9 more
doaj +1 more source
Case Report: The importance of genetic counseling for families with hyperinsulinism
Frontiers in PediatricsCongenital hyperinsulinism (HI) is the most common cause of persistent hypoglycemia in infancy. Genotype-phenotype correlations directly inform medical care for patients.
Victoria R. Sanders +18 more
doaj +1 more source
Dilated Convolutional Neural Networks for Cardiovascular MR Segmentation in Congenital Heart Disease [PDF]
RAMBO 2016, HVSMR 2016. LNCS 10129. pp. 95-102, 2017 We propose an automatic method using dilated convolutional neural networks (CNNs) for segmentation of the myocardium and blood pool in cardiovascular MR (CMR) of patients with congenital heart disease (CHD). Ten training and ten test CMR scans cropped to an ROI around the heart were provided in the MICCAI 2016 HVSMR challenge.
arxiv +1 more source
PLoS ONE, 2020 There is a significant unmet need for a safe and effective therapy for the treatment of children with congenital hyperinsulinism. We hypothesized that amplification of the glucagon signaling pathway could ameliorate hyperinsulinism associated ...
Mangala M Soundarapandian +5 more
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Juvenile hyperinsulinism in a Maine Coon kitten
Journal of Feline Medicine and Surgery Open Reports, 2022 Case summary A 5.5 month-old intact male Maine Coon cat was presented to a referral hospital for a history of muscle fasciculations, lethargy and seizures associated with refractory hypoglycemia.
Matthew Kornya +3 more
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A Computational Framework for Atrioventricular Valve Modeling using Open-Source Software [PDF]
arXiv, 2022 Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has advanced substantially over the last decade and holds particular promise to inform valve repair in small and heterogeneous populations ...
arxiv
Frontiers in EndocrinologyIntroductionCongenital Hyperinsulinism (HI) is a rare disease that causes severe and recurrent hypoglycemia due to dysregulated insulin secretion. HI is the most frequent cause of severe, persistent hypoglycemia in newborns and children.
Tai L. S. Pasquini +17 more
doaj +1 more source
Evaluation of cinematic volume rendering open-source and commercial solutions for the exploration of congenital heart data [PDF]
arXiv, 2023 Detailed anatomical information is essential to optimize medical decisions for surgical and pre-operative planning in patients with congenital heart disease. The visualization techniques commonly used in clinical routine for the exploration of complex cardiac data are based on multi-planar reformations, maximum intensity projection, and volume ...
arxiv
Sex‐specific white matter alterations in children exposed to high pregestational BMI
Obesity, EarlyView.Abstract Objective This study investigated whether exposure to high pregestational BMI (≥ 25 kg/m2) is associated with alterations in white matter microstructure in early childhood, explored sex‐specific effects, and examined associations with cognitive performance. Methods A total of 90 children from the Alberta Pregnancy Outcomes and Nutrition (APrON)
Samson Nivins +5 more
wiley +1 more source
Extreme caution on the use of sirolimus for the congenital hyperinsulinism in infancy patient
Orphanet Journal of Rare Diseases, 2017 We have recently published on the limited effectiveness of sirolimus as a treatment option for hypoglycaemia as a consequence of hyperinsulinism. Our data oppose the view that mTOR inhibitors provide new opportunities for the treatment of patients with ...
Indraneel Banerjee +2 more
doaj +1 more source