CONGENITAL INSENSITIVITY TO PAIN WITH ANHYDROSIS
Gomal Journal of Medical Sciences, 2016 Congenital insensitivity to pain with anhydrosis (CIPA) is a rare genetic disorder characterized by inability to feel pain and temperature, and decreased or absent sweating.
Muhammad shafiq Khan +2 more
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Congenital insensitivity to pain and anhydrosis syndrome
Indian Dermatology Online Journal, 2018 Isa An, Derya Ucmak
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Case report of a 7-year-old CIPA child with multiple debridement's and amputations.
International Journal of Endorsing Health Science Research, 2021 Background: Congenital Insensitivity to Pain (CIPA), otherwise known as Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV), is a rarely occurring autosomal recessive disorder encompassed by a group of hereditary and sensory autonomic ...
Syed Ali Haider Zaidi +7 more
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Congenital insensitivity to pain [PDF]
The Journal of Bone and Joint Surgery. British volume, 2002 We reviewed 13 patients with congenital insensitivity to pain. A quantitative sweat test was carried out in five and an intradermal histamine test in ten. DNA examination showed specific mutations in four patients. There were three clinical presentations: type A, in which multiple infections occurred (five patients); type B, with fractures, growth ...
E, Bar-On +5 more
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Congenital Insensitivity to Pain and Anhidrosis: Dermoscopy of a Rare Genetic Disorder [PDF]
Indian Dermatology Online JournalBalachandra S. Ankad +3 more
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Clinical features for diagnosis and management of patients with PRDM12 congenital insensitivity to pain. [PDF]
, 2016 BACKGROUND: Congenital insensitivity to pain (CIP) is a rare extreme phenotype characterised by an inability to perceive pain present from birth due to lack of, or malfunction of, nociceptors.
Ahmed, Mushtaq +7 more
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Congenital Insensitivity to Pain with Anhidrosis (CIPA) Syndrome; A Rare Genetic Disorder Case Story
Case Reports in Clinical Practice, 2022 Congenital insensitivity to pain with anhidrosis (CIPA) is the subtype four of hereditary sensory and autonomic neuropathy (HASN IV), caused by a defect in the NTRK1 gene and presenting early in life.
Zahra Nafei, Marjan Jafari
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Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
Cell Reports, 2021 Summary: Prdm12 is a key transcription factor in nociceptor neurogenesis. Mutations of Prdm12 cause congenital insensitivity to pain (CIP) from failure of nociceptor development.
Mark A. Landy +4 more
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Congenital insensitivity to pain with anhidrosis and compensatory hyperhidrosis
Indian Journal of Paediatric Dermatology, 2021 Hereditary sensory and autonomic neuropathy is a rare syndrome characterized by congenital insensitivity to pain, temperature changes, and an autonomic nerve formation disorder. We report an 8-year-old boy who presented with late-onset of self-mutilating
Aradhana Rout +3 more
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Linkage between increased nociception and olfaction via a SCN9A haplotype [PDF]
, 2013 Background and Aims: Mutations reducing the function of Nav1.7 sodium channels entail diminished pain perception and olfactory acuity, suggesting a link between nociception and olfaction at ion channel level.
Doehring, Alexandra +4 more
core +2 more sources