Results 201 to 210 of about 2,568 (295)

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

xrdPlanner: exploring area detector geometries for powder diffraction and total scattering experiments. [PDF]

J Synchrotron Radiat
Krause L, Gjørup FH, Jørgensen MRV.
europepmc   +1 more source

A Pollen‐Enhanced Bionic Mechanoreceptor Induced by Asymmetric Ionic Convection in Hydrogel for Sensory‐Augmented Prostheses

Advanced Science, EarlyView.
This work proposed a pollen‐enhanced bionic mechanoreceptor based on ionic convection. Leveraging the ion anchoring effect of the pollen particle, the output performance could be ∼12 times higher than the original state. By employing deep learning models as AI brains, the feasibility of a sensory‐augmented prosthesis consisting of a pollen‐enhanced ...
Zi Hao Guo, Jingyu Deng, Yanzhang Xu, Chenchen Zhou, Yangshi Shao, Xiong Pu, Munho Kim, Namjoon Cho   +7 more
wiley   +1 more source

All-reflective freeform microscope objective for ultra-broadband microscopy. [PDF]

Opt Express
Bauer A, Rolland JP, Clark S, Potma E, Hanninen A.   +4 more
europepmc   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Discrete Isothermic Nets Based on Checkerboard Patterns. [PDF]

Discrete Comput Geom
Dellinger F.
europepmc   +1 more source

Conics for rebellion, 29 July 1830

Conics for rebellion, 29 July ...
Hubbard, Elijah Kent, 1812-1839;
core  

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Molecular blueprints for cleaner air: theoretical insights into Cu(i)-decorated heterocycles for greenhouse gas (CO/CO₂/CH₄) capture. [PDF]

RSC Adv
Bag A, Roymahapatra G.
europepmc   +1 more source

The non-Lefschetz locus of conics

A graded Artinian algebra $A$ has the Weak Lefschetz Property if there exists a linear form $\ell$ such that the multiplication map by $\ell:[A]_i\to [A]_{i+1}$ has maximum rank in every degree.
Marangone, Emanuela
core