Results 41 to 50 of about 13,984 (264)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Earth, Planets and SpaceElectron conics are a distinct type of electron distribution observed in Earth’s magnetosphere, characterized by enhanced fluxes of upgoing electrons at several-keV energies, particularly in the auroral acceleration region.
Hiroki Ishimaru +18 more
doaj +1 more source
Incircular nets and confocal conics
, 2017 We consider congruences of straight lines in a plane with the combinatorics of the square grid, with all elementary quadrilaterals possessing an incircle. It is shown that all the vertices of such nets (we call them incircular or IC-nets) lie on confocal
Akopyan, Arseniy, Bobenko, Alexander I.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Study of Current Driven Electrostatic Instability on the Auroral Zone [PDF]
Journal of Astronomy and Space Sciences, 1986 According to recent satellite observations, strong ion transverse acceleration to the magnetic field(ion conics) has been known. The ion conics may be a result of electrostatic waves frequently observed on the auroral zone.
S. Y. Kim, H. Okuda
doaj
Problems of shape characterization and comparison in bryophytes
Acta Societatis Botanicorum Poloniae, 2014 Shapes of leaves of two liverwort species, viz. Lophozia ventricosa and Lophozia silvicola, were characterized by means of three different methods: polar coordinates, conics, and Fourier series.
Jerzy Szweykowski, Mirosław Krzyśko
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
GIT Compactifications of $M_{0,n}$ from Conics
, 2015 We study GIT quotients parametrizing n-pointed conics that generalize the GIT quotients $(\mathbb{P}^1)^n//SL2$. Our main result is that $\overline{M}_{0,n}$ admits a morphism to each such GIT quotient, analogous to the well-known result of Kapranov for ...
Giansiracusa, Noah, Simpson, Matthew
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source