Results 31 to 40 of about 16,919 (269)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Double-critical graph conjecture for claw-free graphs
Discrete Mathematics, 2017 A connected graph $G$ with chromatic number $t$ is double-critical if $G \backslash \{x, y\}$ is $(t - 2)$-colorable for each edge $xy \in E(G)$. The complete graphs are the only known examples of double-critical graphs. A long-standing conjecture of Erd\H os and Lov sz from 1966, which is referred to as the Double-Critical Graph Conjecture, states ...
Martin Rolek, Zi-Xia Song
openaire +6 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Borcea’s Variance Conjectures on the Critical Points of Polynomials [PDF]
, 2011 Closely following recent ideas of J. Borcea, we discuss various modifications and relaxations of Sendov's conjecture about the location of critical points of a polynomial with complex coefficients. The resulting open problems are formulated in terms of matrix theory, mathematical statistics or potential theory. Quite a few links between classical works
Khavinson, Dmitry +4 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Spirit and Utopia: (German) Idealism as Political Theology [PDF]
, 2015 Can we understand (German) idealism as emancipatory today, after the new realist critique? In this paper, I argue that we can do so by identifying a political theology of revolution and utopia at the theoretical heart of German Idealism.
Chepurin, Kirill
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
, 1999 The traditional attribution of On Sublimity to the third-century critic Cassius Longinus has been rejected by most scholars since the early nineteenth century. The arguments against a third-century date are examined and shown to be unfounded.
Heath, M.
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