Results 31 to 40 of about 345,370 (259)

On the Lazer-McKenna Conjecture Involving Critical and Super-critical Exponents [PDF]

open access: yesMethods and Applications of Analysis, 2008
We prove the Lazer-McKenna conjecture for an elliptic problem of Ambrosetti-Prodi type with critical and supercritical nonlinearities by constructing solutions concentrating on higher dimensional manifolds, under some partially symmetric assumption on the domain.
Dancer, E. N., Yan, Shusen
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

On Some Conjectures Concerning Critical Independent Sets of a Graph [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2016
Let $G$ be a simple graph with vertex set $V(G)$. A set $S\subseteq V(G)$ is independent if no two vertices from $S$ are adjacent. For $X\subseteq V(G)$, the difference of $X$ is $d(X) = |X|-|N(X)|$ and an independent set $A$ is critical if $d(A) = \max \{d(X): X\subseteq V(G) \text{ is an independent set}\}$ (possibly $A=\emptyset$).
openaire   +5 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Actors and Vehicles of Architectural Criticism (4)

open access: yes, 2016
From Satire to Criticism: Comics in Architecture Publications in the 1960s and 1970s Carlos Machado e Moura Faculdade de Arquitectura da Universidade do Porto Cartoons, in the tradition of the graphic satire, have been an acute form of criticism of ...
Mapping Architectural Criticism
core   +1 more source

Ore's conjecture on color-critical graphs is almost true

open access: yesJournal of Combinatorial Theory, Series B, 2014
A graph $G$ is $k$-critical if it has chromatic number $k$, but every proper subgraph of $G$ is $(k-1)$--colorable. Let $f_k(n)$ denote the minimum number of edges in an $n$-vertex $k$-critical graph. We give a lower bound, $f_k(n) \geq F(k,n)$, that is sharp for every $n=1 ({\rm mod} k-1)$. It is also sharp for $k=4$ and every $n\geq 6$.
Alexandr V. Kostochka, Matthew P. Yancey
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

News: CLARA n. 7, "Architectural Criticism and Public Debate", guest edited by Hélène Jannière and Paolo Scrivano, is out!

open access: yes, 2021
The Mapping Architectural Criticism network is pleased to announce the publication of CLARA. Architecture/Recherche n. 7: “Critique architecturale et débat public / Architectural Criticism and Public Debate”, under the scientific direction of Hélène ...
Mapping Architectural Criticism
core  

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