Results 91 to 100 of about 100,362 (316)
The evaluation of the conjugate function of a periodic spline on a uniform mesh
We present an O(N log N) algorithm for the simultaneous evaluation (at all N points of a uniform mesh) of a function conjugate to a periodic spline. The algorithm is based on the attenuation factor theory and makes use of the FFT.
Gutknecht, Martin H.
core +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The equation of the cam profile curve of parallel conjugate cam mechanism and the principle of no-knot condition cubic spine interpolation are introduced,the design error evaluation method of the cam profile curve of the mechanism based on MATLAB is ...
何晶昌
doaj
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Protocol of conjugate evaluation of the biological activity of soils in terms of cellulolytic activity and biological consumption of oxygen. [PDF]
Krechetov PP +3 more
europepmc +1 more source
Oligonucleotides represent a class of molecules that exhibit remarkable therapeutic potential due to their unparalleled target specificity, yet they suffer from limited cellular uptake and lack of tissue selectivity. Extensive research is conducted with cell-penetrating peptides (CPPs) as delivery excipients due to their ability to translocate across ...
Dueholm, Rikke +8 more
openaire +3 more sources
Herein are reported the synthesis of a conjugate of chitosan with l-leucine, the preparation of nanoparticles from both chitosan and the conjugate for use in pulmonary drug delivery, and the in vitro evaluation of toxicity and inflammatory effects of ...
Mohammad D. A. Muhsin (1737304) +5 more
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design, Synthesis, and Antibacterial Evaluation of Rifampicin–Siderophore Conjugates
The growing concern over antibiotic resistance has sparked increased attention toward developing alternative antibiotic strategies. One promising approach, known as the "Trojan horse" strategy, involves the use of siderophores to hijack bacteria's iron transport systems as a way of delivering antibiotics inside the bacterial cell.
Vladyslav Lysenko +5 more
openaire +3 more sources

