Results 91 to 100 of about 84,313 (308)

New step lengths in conjugate gradient methods [PDF]

, 2010
Consider any conjugate gradient method for finding a zero point of a given gradient whose function is implicit. We propose two different types of conditions for selecting the step length using the gradient information only.
Dong, Yunda, Yunda Dong
core   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

The new spectral conjugate gradient method for large-scale unconstrained optimisation

Journal of Inequalities and Applications, 2020
The spectral conjugate gradient methods are very interesting and have been proved to be effective for strictly convex quadratic minimisation. In this paper, a new spectral conjugate gradient method is proposed to solve large-scale unconstrained ...
Li Wang, Mingyuan Cao, Funa Xing, Yueting Yang   +3 more
doaj   +1 more source

Nonlinear conjugate gradient method [PDF]

, 2019
V této práci studujeme nelineární metody sdružených gradientů pro nepodmíněnou optimalizaci. Uvádíme možnosti a limity stávajících metod nepodmíněné optimalizace.
Aleksandr Efremov
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Stability Analysis Of Continuous Conjugate Gradient Method [PDF]

, 2008
Kaedah Conjugate Gradient adalah sangat berguna untuk: menyelesaikan masalah tiada kekangan paling optimum yang berskala besar. Walaubagaimanapun, carlan garis (line search) dalam Kaedah Conjugate Gradient kadang-kadang sukar didapati dan pengiraannya
Harun, Nurzalina
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Flexible Conjugate Gradient [PDF]

, 1999
We analyze the conjugate gradient method with preconditioning slightly variable from one iteration to the next. To maintain the optimal convergence properties, we consider a variant proposed by Axelsson that performs an explicit orthogonalization of the ...
Yvan Notay, Service De Metrologie Nucleaire   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An Adaptive MultiPreconditioned Conjugate Gradient Algorithm [PDF]

SIAM Journal on Scientific Computing, 2016
Summary: This article introduces and analyzes a new adaptive algorithm for solving symmetric positive definite linear systems in cases where several preconditioners are available or the usual preconditioner is a sum of contributions. A new theoretical result allows us to select, at each iteration, whether a classical preconditioned conjugate gradient ...
openaire   +1 more source