Results 111 to 120 of about 265,361 (282)
On three-term conjugate gradient method for optimization problems with applications on COVID-19 model and robotic motion control. [PDF]
Adv Contin Discret Model, 2022 Sulaiman IM +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
On Algorithms Based on Joint Estimation of Currents and Contrast in Microwave Tomography
, 2009 This paper deals with improvements to the contrast source inversion method which is widely used in microwave tomography. First, the method is reviewed and weaknesses of both the criterion form and the optimization strategy are underlined.
Barrière, Paul-André +3 more
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
A New Non-Linear Conjugate Gradient Algorithm for Destructive Cure Rate Model and a Simulation Study: Illustration with Negative Binomial Competing Risks. [PDF]
Commun Stat Simul Comput, 2022 Pal S, Roy S.
europepmc +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Modified Conjugate Gradient Algorithm with Proposed Conjugancy Coefficient
IRAQI JOURNAL OF STATISTICAL SCIENCES, 2011 In this paper, we present modified conjugancy coefficient for the conjugate gradient method based on the (Liu and Storey) method to solve non-linear programming problems. We proved the sufficient descent and the global convergence properties for the proposed algorithm for three cases and we get very good numerical results especially for the large scale
openaire +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source