Results 41 to 50 of about 12,602,940 (286)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Global convergence of two spectral conjugate gradient methods [PDF]

, 2013
Two new nonlinear spectral conjugate gradient methods for solving unconstrained optimization problems are proposed. One is based on the Hestenes and Stiefel (HS) method and the spectral conjugate gradient method. The other is based on a mixed spectral HS-
Ahmad, Tahir, Askaripour, Mohammadreza, Alias, Norma, Ghanbari, Mahdi   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A Novel hybridization of CG-techniques for Solving Unconstrained Optimization Problems

Wasit Journal for Pure Sciences
Conjugate gradient methods are an extremely helpful way for handling large scale non-linear optimization issues. In this paper, based on the three famous Dai-yuan (DY), Liu–Storey (LS)and Conjugate-Descent (CD) conjugate gradient methods, a new hybrid ...
Hawraz Jabbar
doaj   +1 more source

A New Modified Conjugate Gradient for Nonlinear Minimization Problems

Science Journal of University of Zakho, 2022
The conjugate gradient is a highly effective technique to solve the unconstrained nonlinear minimization problems and it is one of the most well-known methods. It has a lot of applications.
Hussein Ageel Khatab, Salah G. Sharef
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

The new spectral conjugate gradient method for large-scale unconstrained optimisation

Journal of Inequalities and Applications, 2020
The spectral conjugate gradient methods are very interesting and have been proved to be effective for strictly convex quadratic minimisation. In this paper, a new spectral conjugate gradient method is proposed to solve large-scale unconstrained ...
Li Wang, Mingyuan Cao, Funa Xing, Yueting Yang   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Two new spectral conjugate gradient algorithms based on Hestenes–Stiefel

Journal of Algorithms & Computational Technology, 2017
The spectral conjugate gradient algorithm, which is a variant of conjugate gradient method, is one of the effective methods for solving unconstrained optimization problems.
Guofang Wang, Rui Shan, Wei Huang, Wen Liu, Jingyi Zhao   +4 more
doaj   +1 more source