Results 41 to 50 of about 66,000 (256)
Numerical: Jurnal Matematika dan Pendidikan Matematika, 2020 This paper develops a Neural network (NN) using conjugate gradient (CG). The modification of this method is in defining the direction of linear search.
Azwar Riza Habibi +2 more
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Symmetric Perry conjugate gradient method [PDF]
Computational Optimization and Applications, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dongyi Liu, Genqi Xu
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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Algorithms, 2021 The conjugate gradient method is one of the most popular methods to solve large-scale unconstrained optimization problems since it does not require the second derivative, such as Newton’s method or approximations.
Zabidin Salleh +3 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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The conjugate gradient method [PDF]
The Leading Edge, 2018 The conjugate gradient method can be used to solve many large linear geophysical problems — for example, least-squares parabolic and hyperbolic Radon transform, traveltime tomography, least-squares migration, and full-waveform inversion (FWI) (e.g., Witte et al., 2018).
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
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A Hybrid of DL and WYL Nonlinear Conjugate Gradient Methods
Abstract and Applied Analysis, 2014 The conjugate gradient method is an efficient method for solving large-scale nonlinear optimization problems. In this paper, we propose a nonlinear conjugate gradient method which can be considered as a hybrid of DL and WYL conjugate gradient methods ...
Shengwei Yao, Bin Qin
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