Results 51 to 60 of about 12,602,940 (286)
Numerical: Jurnal Matematika dan Pendidikan Matematika, 2020 This paper develops a Neural network (NN) using conjugate gradient (CG). The modification of this method is in defining the direction of linear search.
Azwar Riza Habibi +2 more
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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Algorithms, 2021 The conjugate gradient method is one of the most popular methods to solve large-scale unconstrained optimization problems since it does not require the second derivative, such as Newton’s method or approximations.
Zabidin Salleh +3 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Symmetric Perry conjugate gradient method [PDF]
Computational Optimization and Applications, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dongyi Liu, Genqi Xu
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Computing several eigenpairs of Hermitian problems by conjugate gradient iterations
, 2008 The paper is concerned with algorithms for computing several extreme eigenpairs of Hermitian problems based on the conjugate gradient method. We analyse computational strategies employed by various algorithms of this kind reported in the literature and ...
Ovtchinnikov, E.
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The conjugate gradient method [PDF]
The Leading Edge, 2018 The conjugate gradient method can be used to solve many large linear geophysical problems — for example, least-squares parabolic and hyperbolic Radon transform, traveltime tomography, least-squares migration, and full-waveform inversion (FWI) (e.g., Witte et al., 2018).
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source