Results 41 to 50 of about 115,778 (235)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Numerical analysis of a fin-tube plate heat exchanger with winglets [PDF]
In this presented work, numerical analysis of heat transfer and flow characteristic using longitudinal vortex generators (LVGS) in fin and flat tube heat exchanger has been presented. Conjugate heat transfer 3D numerical model has been developed and
Muhsin Al-Juhaishi, Lafta Flayih
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Numerical investigation of forced convection heat transfer from square cylinders in a channel covered by solid wall: Conjugate situation [PDF]
Flow over two isothermal offset square cylinders in a confined channel is simulated for different Reynolds number to reveal the forced convection heat transfer from the heated square cylinders to the ambient fluid for the fixed blockage ratio.
Kanna Rajesh P. +2 more
doaj
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Conjugate heat transfer in circular pipes involves the coupled interaction of turbulent forced convection in the fluid, heat conduction through the pipe wall, and external convection to the ambient, which represents realistic conditions encountered in ...
Bekir Dogan
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Methodology of numerical coupling for transient conjugate heat transfer [PDF]
This paper deals with the construction of a conservative method for coupling a fluid mechanics solver and a heat diffusion code. This method has been designed for unsteady applications. Fluid and solid computational domains are simultaneously integrated
Gressier, Jérémie +2 more
core +3 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

