Results 61 to 70 of about 116,530 (306)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

CFD modeling of heat transfer in a rectangular channel with dimplepin finning [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2013
Using the CFD modeling method, the authors have investigated conjugate heat transfer in a rectangular channel with dimple-pin finning with hight of pins, depth of cavities and Reynolds number values varying in the range, characteristic for heat ...
Spokoiny M. Yu.   +2 more
doaj   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

A synergistic combination of Asymptotic Computational Fluid Dynamics and ANN for the estimation of unknown heat flux from fin heat transfer

open access: yesAlexandria Engineering Journal, 2018
This paper deals with conjugate heat transfer from a rectangular fin. The problem consists of mild steel (250 × 150 × 6 mm) fin placed vertically on aluminium base (250 × 150 × 4 mm).
Harsha Kumar, Gnanasekaran Nagarajan
doaj   +1 more source

A guided artificial bee colony (GABC) heuristic for permutation flowshop scheduling problem (PFSP) [PDF]

open access: yes, 2021
Flowshop is the most common production system in the industry, and there are many documented efforts to improve the performance of the flowshop. The range spreads from the usage of heuristics to metaheuristics, and one of the promising methods is NEH (
Sidek, Noor Azizah
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A numerical method for multiphysics simulations based on hierarchical Cartesian grids

open access: yesJournal of Fluid Science and Technology, 2015
We present a numerical method based on hierarchical Cartesian grids for the simulation of multiphysics problems, here in particular for the conjugate heat transfer between a fluid and a solid.
Gonzalo BRITO GADESCHI   +3 more
doaj   +1 more source

Conjugate Heat Transfer in Diverging Microchannels [PDF]

open access: yes, 2015
A numerical study has been carried out to determine the effects of axial wall conduction during single-phase steady laminar flow of fluid through rectangular diverging (across the length of the channel) cross-sectional microchannel involving conjugate ...
Rajesh Kumar, V
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Low-Concentration Solar-Power Systems Based on Organic Rankine Cycles for Distributed-Scale Applications: Overview and Further Developments [PDF]

open access: yes, 2015
This paper is concerned with the emergence and development of low-to-medium-grade thermal-energy-conversion systems for distributed power generation based on thermo- dynamic vapor-phase heat-engine cycles undergone by organic working uids, namely ...
Markides, CN
core   +2 more sources

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