Results 191 to 200 of about 1,081,297 (374)
NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis
Advanced Science, EarlyView.Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong +18 more
wiley +1 more source
POLYSACCHARIDE CONJUGATE VACCINE RESPONSES IN BONE MARROW TRANSPLANT PATIENTS1
, 1994 Eva C. Guinan +17 more
openalex +1 more source
Pneumoccocal conjugate vaccines [PDF]
International Journal of Infectious Diseases, 2016 openaire +2 more sources
Advanced Microfluidics for Single Cell‐Based Cancer Research
Advanced Science, EarlyView.Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro +10 more
wiley +1 more source
Subclass distribution of IgA antibodies in saliva and serum after immunization withHaemophilus influenzaetype b conjugate vaccines [PDF]
, 1998 M. Kauppi-Korkeila +3 more
openalex +1 more source
Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration
Advanced Science, EarlyView.This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li +11 more
wiley +1 more source
EVALUATION OF A PENTAVALENT CONJUGATED PNEUMOCOCCAL VACCINE IN TODDLERS.▴ 1077 [PDF]
, 1996 Michael E. Pichichero +2 more
openalex +1 more source
Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy
Advanced Science, EarlyView.This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley +1 more source
Medicine and Economics: Accounting for the full benefits of childhood vaccination in South Africa [PDF]
While remarkable gains in health have been achieved since the mid-20th century, these have been unequally distributed, and mortality and morbidity burdens in some regions remain enormous. Of the almost 10 million children under 5 years of age who died in
David E. Bloom +3 more
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