Results 101 to 110 of about 670,162 (341)
LC3 conjugation system in mammalian autophagy
International Journal of Biochemistry and Cell Biology, 2004 Autophagy is the bulk degradation of proteins and organelles, a process essential for cellular maintenance, cell viability, differentiation and development in mammals.
I. Tanida, T. Ueno, E. Kominami
semanticscholar +1 more source
Estimating plasmid conjugation rates: a new computational tool and a critical comparison of methods
bioRxiv, 2020 Plasmids are important vectors for the spread of genes among diverse populations of bacteria. However, there is no standard method to determine the rate at which they spread horizontally via conjugation.
J. Huisman +6 more
semanticscholar +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Angewandte Chemie, 2020 Conjugation of nanoparticles (NP) to the surface of living cells is of interest in the context of exploiting the tissue homing properties of ex vivo engineered T cells for tumor targeted delivery of drugs loaded into NP. Cell surface conjugation requires
Alexander Lamoot +3 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Sustainable Food SystemsThere is a growing demand for plant-based protein ingredients with improved functionality for use in diverse food and nutraceutical applications.
Hina Khan +5 more
doaj +1 more source
Marine Drugs, 2019 Microbial biofilms are considerably more resistant to antibiotics than planktonic cells. It has been reported that chitosan coupling with the aminoglycoside antibiotic streptomycin dramatically disrupted biofilms of several Gram-positive bacteria.
Ruilian Li +6 more
doaj +1 more source
A Fermionic Hodge Star Operator
, 1998 A fermionic analogue of the Hodge star operation is shown to have an explicit operator representation in models with fermions, in spacetimes of any dimension. This operator realizes a conjugation (pairing) not used explicitly in field-theory, and induces
Davis, Alfred, Hubsch, Tristan
core +1 more source
Conjugate Jacobi Series and Conjugate Functions
Journal of Approximation Theory, 1996 The starting point is the notion of conjugacy on a Euclidean \(n\)-space as defined by \textit{E. M. Stein} and \textit{G. Weiss} [Acta Math. 103, 25-62 (1962; Zbl 0097.28501)]. Conjugate Jacobi series is introduced in the sense that the Jacobi harmonic function and the conjugate harmonic function (indicated in the title) satisfy the generalized Cauchy-
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source