Results 91 to 100 of about 670,162 (341)

Sentinel Surveillance Reveals Emerging Daptomycin-Resistant ST736 Enterococcus faecium and Multiple Mechanisms of Linezolid Resistance in Enterococci in the United States

open access: yesFrontiers in Microbiology, 2022
Enterococcus faecalis and faecium with resistance to daptomycin and/or linezolid are emerging globally. We present the genomic characterization of daptomycin- and linezolid-resistant E. faecalis and E. faecium surveillance isolates from the United States,
Amy S. Gargis   +21 more
doaj   +1 more source

CP as a Symmetry of Symmetries

open access: yes, 2017
It is explained that the Standard Model combined charge conjugation and parity transformation (CP) is a simultaneous complex conjugation outer automorphism transformation of gauge and space-time symmetries.
Trautner, Andreas
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

SUMO conjugation – a mechanistic view

open access: yesBiomolecular Concepts, 2017
The regulation of protein fate by modification with the small ubiquitin-related modifier (SUMO) plays an essential and crucial role in most cellular pathways.
A. Pichler   +3 more
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Conjugation Stress of Ligand via Metal Core as the Cause of Changes in the Reactivity of Coordinated 1-Hetero-1,3-Dienes [PDF]

open access: yesУчёные записки Казанского университета: Серия Естественные науки, 2016
Using quantum-chemical calculations carried out for interpretation of the experimentally discovered reactivity of 1-hetero-1,3-dienes that are mono- and bidentally coordinated with the transition metal core, we have revealed that the difference in ...
A.I. Kuramshin   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Through-Space Conjugation: A Thriving Alternative for Optoelectronic Materials

open access: yesCCS Chemistry, 2019
Efficient electronic coupling is the key to constructing optoelectronic functional π systems. Generally, the delocalization of π electrons must comply with the framework constructed by covalent bonds (typically σ bonds), representing classic through-bond
Jinshi Li   +3 more
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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