Results 71 to 80 of about 311,139 (302)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Optimisation of DSF and SOA based phase conjugators by incorporating noise-suppressing fibre gratings

, 1997
We compare the performance of dispersion-shifted-fibre (DSF) and semiconductor-optical-amplifier (SOA) based phase conjugators for a 10 Gb/s non-return-to-zero system with respect to conversion efficiency, noise figure and distortion.
Laming, R.I., Reekie, L., Cole, M.J., Geiger, H., Set, S.Y.   +4 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Maillard reaction-based conjugation of pea protein and prebiotic (polydextrose): optimization, characterization, and functional properties enhancement

Frontiers in Sustainable Food Systems
There is a growing demand for plant-based protein ingredients with improved functionality for use in diverse food and nutraceutical applications.
Hina Khan, Priti Mudgil, Shaikha Ali Salem Alkaabi, Yamna Hamad Salem AlRashdi, Sajid Maqsood, Sajid Maqsood   +5 more
doaj   +1 more source

Synthesis and Evaluation of a Chitosan Oligosaccharide-Streptomycin Conjugate against Pseudomonas aeruginosa Biofilms

Marine Drugs, 2019
Microbial biofilms are considerably more resistant to antibiotics than planktonic cells. It has been reported that chitosan coupling with the aminoglycoside antibiotic streptomycin dramatically disrupted biofilms of several Gram-positive bacteria.
Ruilian Li, Xianghua Yuan, Jinhua Wei, Xiafei Zhang, Gong Cheng, Zhuo A. Wang, Yuguang Du   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Proteotoxic stress reprograms the chromatin landscape of SUMO modification [PDF]

, 2015
The small ubiquitin-like modifier 2 (SUMO-2) is required for survival when cells are exposed to treatments that induce proteotoxic stress by causing the accumulation of misfolded proteins.
Seifert, Anne, Barton, Geoffrey; id_orcid, Schofield, Pieta, Hay, Ronald   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Plasmid conjugation genes.

, 2023
(A) Plasmid pMS7163B conjugation genes as defined by TraDIS. Log2(fold-change–FC) values for insertions in each gene between the pre- and post-conjugation libraries are displayed against pMS7163B.
Minh-Duy Phan (198730), Mark A. Schembri (9330815), Nguyen Thi Khanh Nhu (12872563), Zheng Jie Lian (16425811), David L. Paterson (124677), Steven J. Hancock (12872557)   +5 more
core   +1 more source