Results 31 to 40 of about 32,996 (168)

The evolving trajectory of conjunction use in the ELT research articles

open access: yesFrontiers in Research Metrics and Analytics
The present study was aimed at a diachronic investigation of conjunction as a grammatical cohesive device in ELT research articles. A total number of 100 research articles concentrating on teaching writing skills in the EFL context, and were released in ...
Marzieh Safari, Fatemeh Mahdavirad
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

More on the Categorial Status of (T)àbí in Yorùbá Grammar

open access: yesJournal of Language and Education, 2017
Yorùbá language is one of the major languages spoken in Nigeria. The term is also used to refer to the language and the native speakers. As shown in Oyetade, Yorùbá language is spoken in six states that constitute the southwest of Nigeria – Lagos, Ọ̀
Adeoye Jelili Adewale
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural-Cultural Continuum of Strategic Organizational Changes

open access: yesУправленческие науки, 2016
The purpose of the research is the substantiation of urgency in complex analysis of interdependence and reciprocal conditionality of company’s structural and cultural characteristics in managing strategic organizational changes. The concept of structural-
P. A. Mikhnenko
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On semantic agreement

open access: yesFrontiers in Language Sciences
We discuss semantic agreement, cases in which agreement between a head and a DP seems to drive, or be driven by, interpretive properties of this DP rather than its syntactic properties.
Isabelle Charnavel, Dominique Sportiche
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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