Results 51 to 60 of about 916,358 (306)

The development of conjunction use in advanced L2 speech

Studies in Second Language Learning and Teaching, 2011
The article discusses the results of a longitudinal study of how the use of conjunctions, as an aspect of spoken discourse competence of 13 selected advanced students of English, developed throughout their 3-year English as a foreign language (EFL ...
Marcin Jaroszek
doaj   +1 more source

DIPHTHERITIC CONJUNCTIVITIS : [PDF]

The Lancet, 1873
n ...
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Pulsed flows at the high-altitude cusp poleward boundary, and associated ionospheric convection and particle signatures, during a cluster - FAST - SuperDARN - sondrestrom conjunction under a southwest [PDF]

, 2004
Particle and magnetic field observations during a magnetic conjunction Cluster 1-FAST-Søndrestrøm within the field of view of SuperDARN radars on 21 January 2001 allow us to draw a detailed, comprehensive and self-consistent picture at three heights of ...
Lund, E., S. W. H. Cowley, H. Rème, Balogh, A., E. Sandholt, P., J.-M. Bosqued, W. H. Cowley, S., K. Parks, G., Cerisier, J. C., J.-C. Cerisier, Sauvaud, J.-A., W. Carlson, C., Mobius, E., A. Wild, J., C. W. Carlson, W. Dunlop, M., Bosqued, J.-M., C. J. Farrugia, M. W. Dunlop, Bosqued, J. M., Dunlop, M. W., C. Mouikis, J.-A. Sauvaud, J. Lund, E., Rème, H., D. Kelly, J., Farrugia, C. J., E. Möbius, Wild, J. A., Mouikis, C., J. A. Wild, P. E. Sandholt, J. D. Kelly, A. Balogh, G. K. Parks, Parks, G. K., Sandholt, P. E., J. Farrugia, C., E. J. Lund, Cowley, S. W. H., Kelly, J. D., Carlson, C. W., Cerisier, J.-C.   +42 more
core   +1 more source

Conjunctivitis.

Community eye health, 2005
The conjunctiva is a thin, transparent mucous membrane, which lines the inner surface of the eyelids and covers the sclera (the white part of the eye). The conjunctiva contains glands which produce secretions that help to keep the eyes moist, and antibodies, which reduce infection.
Tissa Senaratne, Clare Gilbert
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source