Results 41 to 50 of about 32,996 (168)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Glossa, 2019 The paper offers a broad overview of several structures that fall under the umbrella term of “partitives”. It surveys previous analyses and proposes a treatment based on two null operators, PART% and PARTPRO, with different syntactic and semantic ...
Michelangelo Falco, Roberto Zamparelli
doaj +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Open Philosophy, 2020 The ontological abyss that separates real objects from sensual objects is one of the central principles of Object-Oriented Ontology (OOO), which has its most explicit and profuse modulation in Timothy Morton’s notion of rift.
Vivaldi Jordi
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Journal of Language and Education, 2017 This paper examines the syntax of sentential conjunction in the Yoruba language with the view of ascertaining the actual syntactic function of sì on which opinions have been polarized in the syntax of Yoruba grammar.
Olabode Abimbola
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
'Mits': oud en stout : een nieuw leven voor voorwaardelijk 'mits'
Brünner Beiträge zur Germanistik und Nordistik, 2016 The old and rather neglected, archaic, formal Dutch word 'mits' (English: 'if and only if') started of as a preposition, evolved in current Dutch to a conjunction, whereas the use as a conditional preposition (quite normal in Belgium) is frowned upon. In
Gert Loosen
doaj
Studies in African Linguistics, 1987 Gender in Chichewa is described as a complete system. First the basic data on gender agreement are presented and it is shown how the available agreement markers correlate with the noun genders (and how the system has changed in the recent past).
Greville G. Corbett, Alfred D. Mtenje
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