Results 51 to 60 of about 2,514,398 (283)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Ev/ اَوْ Bağlacının İfadeye Kattığı Farklı Anlamların Türkçe Meâllere Aktarımı Sorunu

Cumhuriyet İlahiyat Dergisi, 2021
Dilde kullanılan kelimelerin genel olarak bir asıl/temel manası bulunmasının yanı sıra, bu kelimeler zamanla temel anlamının dışında yeni ve özel anlamlar kazanır. Ortaya çıkan bu anlamlar temel anlamdan bütünüyle bağımsız olmaz.
Ahmet Karadağ
doaj   +1 more source

Conjunction revisited

NeuroImage, 2005
The aim of this note is to revisit the analysis of conjunctions in imaging data. We review some conceptual issues that have emerged from recent discussion (Nichols, T., Brett, M., Andersson, J., Wager, T., Poline, J.-B., 2004. Valid Conjunction Inference with the Minimum Statistic.) and reformulate the conjunction of null hypotheses as a conjunction of
Friston, Karl J, Penny, William D, Glaser, Daniel E   +2 more
openaire   +3 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

INTEGRAL observation of hard X-ray variability of the TeV binary LS5039 / RX J1826.2-1450

, 2009
LS 5039/RX J1826.2-1450 is one of the few High Mass X-ray binary systems from which radio and high energy TeV emission has been observed. Moreover, variability of the TeV emission with orbital period was detected.
A. D. Hoffmann, A. Santangelo, A. Segreto, Acciari, Aharonian, Aharonian, Albert, Bednarek, Bird, Bosch-Ramon, Bosch-Ramon, Casares, D. Horns, D. Klochkov, Dubus, Dubus, G. Pühlhofer, Hartman, Lund, Martí, Mas-Hesse, Motch, Paredes, Paredes, Paredes, Perucho, R. Staubert, Ribó, Romero, Romero, Sierpowska-Bartosik, Ubertini, Vedrenne, Winkler   +33 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Accounting for the Semantics of the NP V NP Construction in English

Anglica. An International Journal of English Studies, 2022
In English the NP1 V NP2 construction typically involves arguments that are construed as Agent and Patient, or Subject and Object. It is associated with the notion of transitivity and analyzed accordingly, even when it exhibits only the syntactic ...
Lise Hamelin, Dominique Legallois
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source