Results 41 to 50 of about 1,739,025 (304)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Critical roles of control engineering in the development of intelligent and connected vehicles [PDF]

In recent years, advancements in onboard computing hardware and wireless communication technology have remarkably stimulated the development of intelligent and connected vehicles (ICVs).
Peng Shi, Liu, Yang,, Wang, Liang,, Shi, Peng,, Liang Wang, Yang Liu, Fei, Yang,, Yang Fei   +7 more
core   +1 more source

Modeling and Simulating Urban Traffic Flow Mixed With Regular and Connected Vehicles

IEEE Access, 2021
In the upcoming decades, connected vehicles will join regular vehicles on the road, and the characteristics of traffic flows will change accordingly. To better understand mixed traffic flow (regular vehicles and connected vehicles) characteristics, a ...
Zuping Cao, Lili Lu, Chen Chen, Xu Chen
doaj   +1 more source

A Framework for Lane-Change Maneuvers of Connected Autonomous Vehicles in a Mixed-Traffic Environment

, 2022
In the transition era towards connected autonomous vehicles (CAVs), the sharing of the roadway by CAVs and human-driven vehicles (HDVs) in a mixed-traffic stream is expected to pose safety and flow efficiency concerns even though CAVs may tend to adopt ...
Samuel Labi, Runjia Du, Majed Alinizzi, Sikai Chen, Yujie Li   +4 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Hardware Platform Framework for an Intelligent Vehicle Based on a Driving Brain

Engineering, 2018
The type, model, quantity, and location of sensors installed on the intelligent vehicle test platform are different, resulting in different sensor information processing modules.
Deyi Li, Hongbo Gao
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Connected Vehicles

Vehicle network is a paradigm that presents the concept of a connected vehicle with increased economy and safety via vehicle-to-Everything (V2X) communications. Intelligent transportation systems (ITS) play a critical role in managing all connected vehicle (CV) network technologies on the road worldwide.
S. Bharathi, P. Prakasam
  +5 more sources

Cooperative Merging Strategy Between Connected Autonomous Vehicles in Mixed Traffic

IEEE Open Journal of Intelligent Transportation Systems, 2022
In this work we propose a new cooperation strategy between connected autonomous vehicles in on-ramps merging scenarios and we implement the cut-in risk indicator (CRI) to investigate the safety effect of the proposed strategy.
Eleonora Andreotti, Selpi, Maytheewat Aramrattana   +2 more
doaj   +1 more source