Results 51 to 60 of about 1,739,025 (304)

Driving with Sharks: Rethinking Connected Vehicles with Vehicle Cybersecurity [PDF]

open access: yesIEEE Vehicular Technology Magazine, 2017
In a public service announcement on March 17, 2016, the Federal Bureau of Investigation (FBI) jointly with the Department of Transportation and the National Highway Traffic Safety Administration, released a warning over the increasing vulnerability of motor vehicles to remote exploits . Engine shutdown, disable brakes and door locks are few examples of
Mahmoud Hashem Eiza, Qiang Ni
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Symbolic Imitation Learning: From Black-Box to Explainable Driving Policies

open access: yesApplied Sciences
Current imitation learning approaches, predominantly based on deep neural networks (DNNs), offer efficient mechanisms for learning driving policies from real-world datasets.
Iman Sharifi   +2 more
doaj   +1 more source

Floating Car Data Adaptive Traffic Signals: A Description of the First Real-Time Experiment with “Connected” Vehicles

open access: yes, 2020
The future of traffic management will be based on “connected” and “autonomous” vehicles. With connected vehicles it is possible to gather real-time information.
Demetrio Festa   +4 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

STGFormer: Spatio-Temporal Graph Transformer for Traffic Flow Prediction in Sparse-Sensing Scenarios

open access: yesSensors
With the continuous improvement in intelligent transportation and data perception levels, determining how to achieve high-precision and generalizable traffic flow prediction based on historical traffic data has become an important issue in intelligent ...
Jin Zhang   +4 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Research and prospect of intelligent connected vehicle test scheme

open access: yesDianxin kexue, 2023
The comprehensive test and evaluation of intelligent connected vehicles is an important guarantee for the safety of intelligent connected vehicles on the road and the smooth landing of the industry.Based on the test status, test technology path, test ...
Dongsheng WU   +3 more
doaj   +2 more sources

Other title: Interstate Reciprocity Agreement Between the State of Nebraska and the State of Kansas

open access: yes, 2010
application/pdf Date of last signature: 4/28/10.--Page 7. Includes First Amendment to the Declaration of Interstate Reciprocity Agreement Between the State of Nebraska and the State of Kansas. Legal Review Completed: 4/29/2010."This Reciprocity Agreement
Kansas. Division of Vehicles.
core   +1 more source

Home - About - Disclaimer - Privacy